PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25934339-1 2015 The purpose of this study is to evaluate the influence of germline polymorphisms of cytochrome P450 (CYP450) on objective response, progression-free survival (PFS) and overall suruvival (OS) in metastatic colorectal cancer (mCRC) receiving the combination chemotherapy of irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI). Leucovorin 304-314 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 84-99 25934339-1 2015 The purpose of this study is to evaluate the influence of germline polymorphisms of cytochrome P450 (CYP450) on objective response, progression-free survival (PFS) and overall suruvival (OS) in metastatic colorectal cancer (mCRC) receiving the combination chemotherapy of irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI). Leucovorin 304-314 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 101-107