PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21464406-1 2011 PURPOSE: PTK787/ZK 222584 (PTK/ZK; vatalanib), an orally active, multitargeted angiogenesis inhibitor, has shown tolerability and promising activity in early-phase studies, which led to a phase III trial in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4). Leucovorin 255-265 protein tyrosine kinase 2 beta Homo sapiens 27-33