PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2559853-4 1989 The direct acting stimulants of soluble guanylate cyclase, sodium nitroprusside and SIN-1 (3-morpholino-sydnonimine), also increased the cGMP content of endothelial cells by 9.4 and 7.2 times, respectively. Nitroprusside 59-79 guanylate cyclase Bos taurus 40-57 9426959-4 1997 METHODS: The effects of sodium nitroprusside (SNP), as a nitric oxide donor, methylene blue, as an inhibitor of guanylate cyclase, and 8-bromo-cyclic GMP on the bovine ciliary muscle contracted with ET-1 were examined. Nitroprusside 24-44 guanylate cyclase Bos taurus 112-129 9426959-6 1997 RESULTS: Sodium nitroprusside (SNP) produced a concentration-dependent relaxation, which was significantly (p < 0.005) augmented by 10(-5) M 3-isobutyl-1-methylxanthine (IBMX) and significantly (p < 0.005) attenuated by 3 x 10(-5) M methylene blue as an inhibitor of guanylate cyclase. Nitroprusside 9-29 guanylate cyclase Bos taurus 273-290 9106063-3 1997 The activity of GC was linearly dependent on the amount of cGMP produced in the presence of sodium nitroprusside. Nitroprusside 92-112 guanylate cyclase Bos taurus 16-18 2573403-7 1989 In the absence of endothelial cells, nitric oxide (NO, 1-2 microM), arachidonic acid (AA, 3-30 microM) or sodium nitroprusside (SNP, 1-100 microM) stimulated guanylate cyclase. Nitroprusside 106-126 guanylate cyclase Bos taurus 158-175 7509393-8 1994 We conclude that IFN-gamma induces a marked increase in release of arterial-derived nitric oxide resulting in a desensitization of guanylate cyclase, which contributes to a decrease in relaxation to bradykinin and nitroprusside. Nitroprusside 214-227 guanylate cyclase Bos taurus 131-148 1978674-1 1990 In the presence of oxidized low-density lipoprotein the stimulatory effects of nitric oxide, sodium nitroprusside and S-nitrosoglutathione on soluble guanylate cyclase partially purified from bovine platelets were diminished in a concentration-dependent manner with IC50 values around 100 micrograms total cholesterol/ml. Nitroprusside 93-113 guanylate cyclase Bos taurus 150-167 6118808-5 1981 Dose-dependent stimulation of guanylate cyclase was found in a particulate preparation of parathyroid cells; activity was maximal at 10(-4)M nitroprusside while higher concentrations appeared to inhibit the enzyme. Nitroprusside 141-154 guanylate cyclase Bos taurus 30-47 6150599-3 1984 The stimulatory action of nitroprusside (NP) or GTN/cysteine on guanylate cyclase (GC) was reduced by 50-60% in GTN-tolerant vessels as compared to control vessels. Nitroprusside 26-39 guanylate cyclase Bos taurus 64-81 6150599-3 1984 The stimulatory action of nitroprusside (NP) or GTN/cysteine on guanylate cyclase (GC) was reduced by 50-60% in GTN-tolerant vessels as compared to control vessels. Nitroprusside 26-39 guanylate cyclase Bos taurus 83-85 6150599-3 1984 The stimulatory action of nitroprusside (NP) or GTN/cysteine on guanylate cyclase (GC) was reduced by 50-60% in GTN-tolerant vessels as compared to control vessels. Nitroprusside 41-43 guanylate cyclase Bos taurus 64-81 6150599-3 1984 The stimulatory action of nitroprusside (NP) or GTN/cysteine on guanylate cyclase (GC) was reduced by 50-60% in GTN-tolerant vessels as compared to control vessels. Nitroprusside 41-43 guanylate cyclase Bos taurus 83-85 6134553-11 1983 Several observations indicated that neither NO-thiol complexes nor [Fe(CN)5NO]-3 were the proximate moieties responsible for activation of guanylate cyclase by nitroprusside and related agents, as has been previously suggested. Nitroprusside 160-173 guanylate cyclase Bos taurus 139-156 6114859-0 1981 Purification of a soluble, sodium-nitroprusside-stimulated guanylate cyclase from bovine lung. Nitroprusside 27-47 guanylate cyclase Bos taurus 59-76 6114859-1 1981 A soluble, sodium-nitroprusside-stimulated guanylate cyclase as been purified from bovine lung by DEAE-cellulose chromatography, ammonium sulfate precipitation, chromatography on Blue Sepharose CL-6B and preparative gel electrophoresis. Nitroprusside 11-31 guanylate cyclase Bos taurus 43-60 6105889-2 1980 However, guanylate cyclase activation by nitroprusside or nitric oxide did not require the addition of thiols or ascorbate. Nitroprusside 41-54 guanylate cyclase Bos taurus 9-26 6105889-6 1980 Guanylate cyclase activation by S-nitrosothiols resembled that by nitric oxide and nitroprusside in that activation was inhibited by methemoglobin, ferricyanide and methylene blue. Nitroprusside 83-96 guanylate cyclase Bos taurus 0-17 6105889-9 1980 Moreover, these findings suggest that S-nitrosothiols could act as intermediates in the activation of guanylate cyclase by glyceryl trinitrate, NaNO2 and possibly nitroprusside. Nitroprusside 163-176 guanylate cyclase Bos taurus 102-119