PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17803971-13 2007 The presence of the L-type Ca(2+) channel inhibitor, nifedipine (10 microM), partially inhibited 17beta-estradiol- and PPT-induced increase in phosphorylated ERK expression, whereas it induced a complete inhibition of DPN-induced increase in ERK phosphorylation. NAD 218-221 tachykinin precursor 1 Homo sapiens 119-122 28832634-5 2017 NKA enzyme activity was determined by NADH-linked methods and immunoblotting of NKA alpha1-, beta1-isoform, and E-cadherin were performed to evaluate protein expression. NAD 38-42 tachykinin precursor 1 Homo sapiens 0-3 33672651-6 2021 We treated cells with 17beta-estradiol (E2), 1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole (PPT) an estrogen receptor (ER) alpha (ERalpha) agonist, or 2,3-bis(4-hydroxyphenyl)-propionitrile (DPN), an ERbeta agonist. NAD 194-197 tachykinin precursor 1 Homo sapiens 95-98 24356876-8 2014 In contrast, 17beta-estradiol or DPN relaxed placental arteries (maximum relaxation to 42 +- 1.1 or 47.6 +- 6.53% of preconstriction, respectively) to a lesser extent than myometrial arteries (to 0.03 +- 0.03 or 8.0 +- 1.0%) and in an endothelial-independent manner whereas PPT was without effect. NAD 33-36 tachykinin precursor 1 Homo sapiens 274-277 19487957-5 2009 However, when NKA activity of the alpha1beta1 isoform was measured in membrane preparations from human kidney (reduced form of nicotinamide adenine dinucleotide-coupled assay, n = 3), a concentration-dependent full inhibition of the activity was induced by 8-methoxycoumestrol (IC50: 90 +/- 97 nM), similar to that observed for classical cardiac glycosides digitoxin, digoxin, methyldigoxin, and beta-acetyldigoxin (IC50 = 287 +/- 190 nM, 409 +/- 171 nM, 282 +/- 482 nM, 587 +/- 135 nM, P > 0.05). NAD 127-160 tachykinin precursor 1 Homo sapiens 14-17