PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31434939-7	2019	VSMC stimulation with GSNO, a nitric oxide analogue or with 8-br-cGMP, but not with 8-br-cAMP, up-regulated PDE5 and NOTCH-3 protein levels, indicating a negative feedback loop to protect the arterial wall from excessive relaxation.	S-Nitrosoglutathione	22-26	phosphodiesterase 5A	Homo sapiens	108-112	
23764893-6	2013	The NO donor S-nitrosoglutathione (GSNO) caused an increase in PDE5 activity and intra- and extracellular cGMP levels in both fundus and antrum.	S-Nitrosoglutathione	13-33	phosphodiesterase 5A	Homo sapiens	63-67	
23764893-6	2013	The NO donor S-nitrosoglutathione (GSNO) caused an increase in PDE5 activity and intra- and extracellular cGMP levels in both fundus and antrum.	S-Nitrosoglutathione	35-39	phosphodiesterase 5A	Homo sapiens	63-67	
23764893-9	2013	Consistent with the higher expression and activity levels of PDE5 and MRP5, GSNO-induced PKG activity and muscle relaxation were significantly lower in muscle cells from fundus compared with antrum.	S-Nitrosoglutathione	76-80	phosphodiesterase 5A	Homo sapiens	61-65	
18204475-5	2008	KEY RESULTS: GSNO stimulated PDE5 phosphorylation and activity and increased cGMP levels in gastric smooth muscle cells.	S-Nitrosoglutathione	13-17	phosphodiesterase 5A	Homo sapiens	29-33	
18204475-6	2008	Concurrent activation of cells with ACh augmented GSNO-stimulated PDE5 phosphorylation and activity, and attenuated cGMP levels.	S-Nitrosoglutathione	50-54	phosphodiesterase 5A	Homo sapiens	66-70