PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34904016-0	2021	Quercetin Reduces Oxidative Stress and Apoptosis by Inhibiting HMGB1 and Its Translocation, Thereby Alleviating Liver Injury in ACLF Rats.	Quercetin	0-9	high mobility group box 1	Rattus norvegicus	63-68	
34904016-3	2021	Our previous studies have shown that quercetin (Que) exerts anti-oxidant and anti-apoptotic effects by inhibiting HMGB1 in vitro.	Quercetin	37-46	high mobility group box 1	Rattus norvegicus	114-119	
34904016-3	2021	Our previous studies have shown that quercetin (Que) exerts anti-oxidant and anti-apoptotic effects by inhibiting HMGB1 in vitro.	Quercetin	48-51	high mobility group box 1	Rattus norvegicus	114-119	
33318415-5	2021	Quercetin markedly increased the thickness of the retinal cell layer, increased the number of ganglion cells, and decreased the overexpression of the pro-inflammatory factors interleukin-1beta, interleukin-18, interleukin-6 and tumor necrosis factor-alpha in the retinal tissue as well as the overexpression of high mobility group box-1 and the overactivation of the NLRP3 inflammasome.	Quercetin	0-9	high mobility group box 1	Rattus norvegicus	311-336	
34661255-1	2021	OBJECTIVE: To explore the therapeutic effects of quercetin on rats with encephalitis, especially on cell apoptosis, and the levels of HMGB-1 and TLR-4.	Quercetin	49-58	high mobility group box 1	Rattus norvegicus	134-140	
34661255-7	2021	CONCLUSIONS: Quercetin is effective in treating encephalitis rats possibly through inhibition of neuronal cell apoptosis and level of HMGB-1 and TLR-4.	Quercetin	13-22	high mobility group box 1	Rattus norvegicus	134-140	
33617360-11	2021	Additionally, quercetin blocked inflammatory mediators HMGB-1 and IFN-gamma, inhibiting activation of the NF-kappaB/TLR-4 axis.	Quercetin	14-23	high mobility group box 1	Rattus norvegicus	55-61	
29887944-0	2018	Quercetin attenuates myocardial ischemia-reperfusion injury via downregulation of the HMGB1-TLR4-NF-kappaB signaling pathway.	Quercetin	0-9	high mobility group box 1	Rattus norvegicus	86-91	
31377749-0	2019	Quercetin Exerted Protective Effects in a Rat Model of Sepsis via Inhibition of Reactive Oxygen Species (ROS) and Downregulation of High Mobility Group Box 1 (HMGB1) Protein Expression.	Quercetin	0-9	high mobility group box 1	Rattus norvegicus	132-157	
31377749-0	2019	Quercetin Exerted Protective Effects in a Rat Model of Sepsis via Inhibition of Reactive Oxygen Species (ROS) and Downregulation of High Mobility Group Box 1 (HMGB1) Protein Expression.	Quercetin	0-9	high mobility group box 1	Rattus norvegicus	159-164	
31377749-14	2019	The effects of quercetin were also examined on the expression of the High mobility group box 1 (HMGB1) protein in septic rats.	Quercetin	15-24	high mobility group box 1	Rattus norvegicus	69-94	
31377749-14	2019	The effects of quercetin were also examined on the expression of the High mobility group box 1 (HMGB1) protein in septic rats.	Quercetin	15-24	high mobility group box 1	Rattus norvegicus	96-101	
31377749-15	2019	The results showed that quercetin caused a significant decrease in HMGB1 protein levels.	Quercetin	24-33	high mobility group box 1	Rattus norvegicus	67-72