PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25971889-16 2015 In addition, quercetin suppressed the phosphorylation of c-Met downstream molecules including Gab1 (GRB2-associated-binding protein 1), FAK (Focal Adhesion Kinase) and PAK (p21-activated kinases). Quercetin 13-22 protein tyrosine kinase 2 Homo sapiens 136-139 25971889-16 2015 In addition, quercetin suppressed the phosphorylation of c-Met downstream molecules including Gab1 (GRB2-associated-binding protein 1), FAK (Focal Adhesion Kinase) and PAK (p21-activated kinases). Quercetin 13-22 protein tyrosine kinase 2 Homo sapiens 141-162 25971889-17 2015 More importantly, overexpression of FAK or PAK significantly reduced the inhibitory effect of quercetin on the migration of the melanoma cells. Quercetin 94-103 protein tyrosine kinase 2 Homo sapiens 36-39 25793633-3 2015 In addition, we found that quercetin significantly decreased the phosphorylation of ERK1/2 and FAK, a downstream ERK signaling protein. Quercetin 27-36 protein tyrosine kinase 2 Homo sapiens 95-98 25793633-5 2015 Our findings thus indicate that quercetin inhibits healing in the scratch-wound model of primary astrocytes in two ways: blockade of the G1 to S phase cell cycle transition and inhibition of the ERK/FAK signaling pathway, which may contribute toward decreasing astroglial scar formation in vivo. Quercetin 32-41 protein tyrosine kinase 2 Homo sapiens 199-202 16158939-4 2005 MiaPaCa-2 cells, treated with luteolin (Lu) and quercetin (Qu), were used to dampen FAK phosphorylation and protein expression by parallel suppression of cell migration ability. Quercetin 48-57 protein tyrosine kinase 2 Homo sapiens 84-87 16158939-7 2005 Our results show that FAK functions as a key regulator of cell migration, and that FAK activity can be suppressed by specific FAK siRNA, and by luteolin and quercetin. Quercetin 157-166 protein tyrosine kinase 2 Homo sapiens 22-25 16158939-7 2005 Our results show that FAK functions as a key regulator of cell migration, and that FAK activity can be suppressed by specific FAK siRNA, and by luteolin and quercetin. Quercetin 157-166 protein tyrosine kinase 2 Homo sapiens 83-86 16158939-7 2005 Our results show that FAK functions as a key regulator of cell migration, and that FAK activity can be suppressed by specific FAK siRNA, and by luteolin and quercetin. Quercetin 157-166 protein tyrosine kinase 2 Homo sapiens 83-86 30700983-5 2018 Pre-treatment with quercetin, known for its anti-oxidant and anti-inflammatory activity, reduced bacterial infection to Caco-2 cells, which might be partially via interfering integrin beta1 and FAK association augmented by E. coli O157:H7. Quercetin 19-28 protein tyrosine kinase 2 Homo sapiens 194-197