PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20728021-0 2010 Quercetin up-regulates paraoxonase 1 gene expression via sterol regulatory element binding protein 2 that translocates from the endoplasmic reticulum to the nucleus where it specifically interacts with sterol responsive element-like sequence in paraoxonase 1 promoter in HuH7 liver cells. Quercetin 0-9 MIR7-3 host gene Homo sapiens 271-275 20728021-5 2010 Evaluation of the binding of biotin-labeled sterol responsive element (SRE)-like element of the PON1 promoter to the nuclear extract from the 24-hour quercetin (20 micromol/L)-treated HuH7 cells by electrophoretic mobility shift assay revealed that the SREBP2 specifically binds to the SRE-like element that was abolished by prior incubation with anti-SREBP2 or significantly decreased by 200-fold molar excess of unlabeled SRE-like sequence. Quercetin 150-159 MIR7-3 host gene Homo sapiens 184-188 12508355-6 2003 RESULTS: Quercetin was found to suppress proliferation of human HCC cell lines BEL-7402, HuH-7 and HLE, with peak suppression at 50 micromol/L quercetin. Quercetin 9-18 MIR7-3 host gene Homo sapiens 89-94 12508355-6 2003 RESULTS: Quercetin was found to suppress proliferation of human HCC cell lines BEL-7402, HuH-7 and HLE, with peak suppression at 50 micromol/L quercetin. Quercetin 143-152 MIR7-3 host gene Homo sapiens 89-94 34326886-13 2021 Our study demonstrated that the anti-HCC proliferation activity of EH is mainly exerted by two active ingredients (quercetin and wedelolactone), which inhibit the proliferation of HCC cells (HepG2 and Huh-7) by inhibiting PI3K-AKT signaling. Quercetin 115-124 MIR7-3 host gene Homo sapiens 201-206 27546480-4 2016 In both cell types, quercetin significantly decreased i) the viral genome replication; ii) the production of infectious HCV particles and iii) the specific infectivity of the newly produced viral particles (by 85% and 92%, Huh7.5 and PHH respectively). Quercetin 20-29 MIR7-3 host gene Homo sapiens 223-227 15169886-3 2004 In the HuH7 human hepatoma cell line, PON-1 activity and mRNA levels were increased by dietary polyphenolic compounds such as quercetin but also by toxic ligands of the aryl hydrocarbon receptor (AhR) such as 3-methylcholanthrene (3-MC). Quercetin 126-135 MIR7-3 host gene Homo sapiens 7-11