PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15749994-0 2005 Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides. Quercetin 79-88 ATP binding cassette subfamily G member 2 Rattus norvegicus 34-39 15749994-0 2005 Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides. Quercetin 79-88 ATP binding cassette subfamily G member 2 Rattus norvegicus 40-45 15749994-8 2005 When intestinal Bcrp1 was inhibited by FTC in Mrp2-deficient rats, total plasma concentrations of quercetin and its methylated metabolite isorhamnetin after 30 min of perfusion were more than twice that of controls (12.3 +/- 1.5 versus 5.6 +/- 1.3 muM; p < 0.01), whereas uptake of free quercetin from the intestinal lumen was not affected. Quercetin 98-107 ATP binding cassette subfamily G member 2 Rattus norvegicus 16-21 15749994-8 2005 When intestinal Bcrp1 was inhibited by FTC in Mrp2-deficient rats, total plasma concentrations of quercetin and its methylated metabolite isorhamnetin after 30 min of perfusion were more than twice that of controls (12.3 +/- 1.5 versus 5.6 +/- 1.3 muM; p < 0.01), whereas uptake of free quercetin from the intestinal lumen was not affected. Quercetin 290-299 ATP binding cassette subfamily G member 2 Rattus norvegicus 16-21 15749994-10 2005 In conclusion, Bcrp1 limits net intestinal absorption of quercetin by pumping quercetin glucuronides back into the lumen. Quercetin 57-66 ATP binding cassette subfamily G member 2 Rattus norvegicus 15-20