PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16158213-1 2005 PURPOSE: The aim of this study was to develop quantitative structure-activity/pharmacokinetic relationships (QSAR/QSPKR) for a series of synthesized 1,4-dihydropyridines (DHPs) and pyridines as P-glycoprotein (P-gp) inhibitors. Pyridines 160-169 ATP binding cassette subfamily B member 1 Homo sapiens 194-208 16158213-1 2005 PURPOSE: The aim of this study was to develop quantitative structure-activity/pharmacokinetic relationships (QSAR/QSPKR) for a series of synthesized 1,4-dihydropyridines (DHPs) and pyridines as P-glycoprotein (P-gp) inhibitors. Pyridines 160-169 ATP binding cassette subfamily B member 1 Homo sapiens 210-214 16158213-10 2005 CONCLUSION: QSAR/QSPKR models were developed, and the QSAR models were capable of identifying synthesized 1,4-DHPs and pyridines with potent P-gp inhibition and reduced Ca2+ channel binding. Pyridines 119-128 ATP binding cassette subfamily B member 1 Homo sapiens 141-145