PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18292680-12 2008 A loss-of-function mutation of the Apaf-1 homolog CED-4 blocked the preconditioning effect of isoflurane, but mutation of the downstream caspase CED-3 did not. Isoflurane 94-104 Cell death protein 4 Caenorhabditis elegans 50-55