PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24037316-0	2013	Critical role of interleukin-11 in isoflurane-mediated protection against ischemic acute kidney injury in mice.	Isoflurane	35-45	interleukin 11	Mus musculus	17-31	
24037316-3	2013	In this study, the authors tested the hypothesis that isoflurane protects against ischemic acute kidney injury by direct induction of renal tubular IL-11 synthesis.	Isoflurane	54-64	interleukin 11	Mus musculus	148-153	
24037316-6	2013	Mice anesthetized with isoflurane showed significantly increased kidney IL-11 messenger RNA (13.8 +- 2 fold over carrier gas group, N = 4) and protein (31 +- 9 vs. 18 +- 2 pg/mg protein or approximately 80% increase, N = 4) expression compared with pentobarbital-anesthetized mice, and this increase was also attenuated by a TGF-beta1-neutralizing antibody.	Isoflurane	23-33	interleukin 11	Mus musculus	72-77	
24037316-7	2013	Furthermore, isoflurane-mediated renal protection in IL-11R wild-type mice was absent in IL-11R-deficient mice or in IL-11R wild-type mice treated with IL-11-neutralizing antibody (N = 4-6).	Isoflurane	13-23	interleukin 11	Mus musculus	53-58	
24037316-8	2013	CONCLUSION: In this study, the authors suggest that isoflurane induces renal tubular IL-11 via TGF-beta1 signaling to protect against ischemic acute kidney injury.	Isoflurane	52-62	interleukin 11	Mus musculus	85-90