PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21930122-7	2011	The number of CHOP and caspase-12 positive neurons significantly increased by 138% and 147% respectively in the hippocampus of isoflurane-exposed pups, as well as the levels of CHOP and caspase-12 protein.	Isoflurane	127-137	DNA-damage inducible transcript 3	Rattus norvegicus	14-18	
21930122-10	2011	Our study further showed that the up-regulation of CHOP and caspase-12 may contribute to isoflurane-induced neuron apoptosis.	Isoflurane	89-99	DNA-damage inducible transcript 3	Rattus norvegicus	51-55	
26162760-9	2015	We found that isoflurane triggered ERS as evidenced by increased phosphorylation of eukaryotic initiation factor (EIF) 2alpha, and increased expression of 78-kDa glucose-regulated protein (GRP78), activating transcription factor (ATF) 4 and C/EBP homologous protein (CHOP).	Isoflurane	14-24	DNA-damage inducible transcript 3	Rattus norvegicus	241-265	
26162760-9	2015	We found that isoflurane triggered ERS as evidenced by increased phosphorylation of eukaryotic initiation factor (EIF) 2alpha, and increased expression of 78-kDa glucose-regulated protein (GRP78), activating transcription factor (ATF) 4 and C/EBP homologous protein (CHOP).	Isoflurane	14-24	DNA-damage inducible transcript 3	Rattus norvegicus	267-271