PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6301285-3	1983	Metoprolol, a beta 1-adrenoceptor antagonist, given in the renal artery, did not affect the decrease in urinary sodium excretion but attenuated the increase in renin secretion rate, from 1,764 +/- 525 to 412 +/- 126 ng/min (70 +/- 8%).	Metoprolol	0-10	renin	Canis lupus familiaris	160-165	
19073902-3	2009	We hypothesized that in this setting, renin secretion and renin-dependent sodium excretion are controlled by via the renal nerves and therefore are eliminated or reduced by blocking the action of norepinephrine on the juxtaglomerular cells with the beta1-receptor antagonist metoprolol.	Metoprolol	275-285	renin	Canis lupus familiaris	38-43	
19073902-3	2009	We hypothesized that in this setting, renin secretion and renin-dependent sodium excretion are controlled by via the renal nerves and therefore are eliminated or reduced by blocking the action of norepinephrine on the juxtaglomerular cells with the beta1-receptor antagonist metoprolol.	Metoprolol	275-285	renin	Canis lupus familiaris	58-63	
6096280-5	1984	However, after metoprolol, a beta 1-adrenergic blocking agent that blocks the rise in plasma renin activity during exercise, swimming causes a threefold increase in albuminuria (P less than 0.01).	Metoprolol	15-25	renin	Canis lupus familiaris	93-98	
6269043-7	1981	Metoprolol, alone, reduced the renin release response to high level RNS by 37 +/- 14% (P less than 0.05).	Metoprolol	0-10	renin	Canis lupus familiaris	31-36	
6269043-11	1981	Addition of metoprolol to phenoxybenzamine practically abolished the renal vasoconstrictor response and the renin release response to high level RNS; 94 +/- 4% (P less than 0.01).	Metoprolol	12-22	renin	Canis lupus familiaris	108-113	
6301285-5	1983	Addition of metoprolol to indomethacin-pretreated dogs attenuated the increase in renin secretion rate from 833 +/- 327 to 94 +/- 60 ng/min (86 +/- 10%).	Metoprolol	12-22	renin	Canis lupus familiaris	82-87	
6107894-5	1980	The renin release response was almost abolished by 0.5 mg/kg of metoprolol or dl-propranolol but unaffected by 0.5 mg/kg of d-propranolol.	Metoprolol	64-74	renin	Canis lupus familiaris	4-9	
6107894-6	1980	The increase in renin release to high level RNS was equally reduced by 33% by 0.5 mg/kg and 2.0 mg/kg of metoprolol.	Metoprolol	105-115	renin	Canis lupus familiaris	16-21