PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30008820-4	2018	Treatment with the ADRB2 antagonists ICI118,551 and metoprolol significantly inhibited the growth of human HCC cells.	Metoprolol	52-62	adrenoceptor beta 2	Homo sapiens	19-24	
23261005-9	2013	In conclusion, these data indicate that the selected SNPs of beta(1)-AR and beta(2)-AR genes influence HR response to metoprolol in patients who undergo coronary computed tomographic angiography.	Metoprolol	118-128	adrenoceptor beta 2	Homo sapiens	76-86	
23489141-0	2013	PDE3, but not PDE4, reduces beta1 - and beta2-adrenoceptor-mediated inotropic and lusitropic effects in failing ventricle from metoprolol-treated patients.	Metoprolol	127-137	adrenoceptor beta 2	Homo sapiens	40-58	
2179287-6	1990	Using clinically relevant doses, metoprolol CR/ZOK affects beta 2-adrenoceptor-mediated functions (e.g., broncho-dilatation in asthmatics) less than tablets do.	Metoprolol	33-43	adrenoceptor beta 2	Homo sapiens	59-78	
1591462-0	1992	Quantification of metoprolol beta 2-adrenoceptor antagonism in asthmatic patients by pharmacokinetic-pharmacodynamic modelling.	Metoprolol	18-28	adrenoceptor beta 2	Homo sapiens	29-48	
1591462-4	1992	Beta 2-adrenoceptor mediated changes of plasma potassium and FEV1 were related to plasma concentrations of terbutaline and racemic metoprolol.	Metoprolol	131-141	adrenoceptor beta 2	Homo sapiens	0-19	
17671401-0	2007	Beta-2-adrenergic receptor polymorphisms and changes in lipids induced by metoprolol.	Metoprolol	74-84	adrenoceptor beta 2	Homo sapiens	0-26	
1848636-3	1991	We investigated if the latter also applies to the beta-2 adrenoceptor antagonism by metoprolol.	Metoprolol	84-94	adrenoceptor beta 2	Homo sapiens	50-69	
2565392-1	1989	We studied the competitive interaction of terbutaline and two beta blockers, metoprolol and oxprenolol, with different cardioselectivity for the beta-2 adrenoceptor.	Metoprolol	77-87	adrenoceptor beta 2	Homo sapiens	145-164	
2836204-8	1988	Thus, the new CR formulation of metoprolol caused fewer adverse effects on beta 2-adrenoceptor mediated bronchodilatation than a clinically equivalent dose of atenolol.	Metoprolol	32-42	adrenoceptor beta 2	Homo sapiens	75-94	
6134510-8	1983	Beta-blockers, particularly propranolol and metoprolol, with which we have the most experience, work via beta 2 adrenoceptor blockade in the heart.	Metoprolol	44-54	adrenoceptor beta 2	Homo sapiens	105-124