PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12574206-5 2003 The NF-kappa B inhibitor, N-tosyl-L-phenylalanine chloromethyl ketone, reduced TNFalpha-induced IL-8 gene and protein expression. Tosylphenylalanyl Chloromethyl Ketone 26-69 C-X-C motif chemokine ligand 8 Homo sapiens 96-100 26418512-4 2016 Augmented IL-8 secretion by Ca9-22 cells was blocked by the NF-kappaB inhibitor L-1-4"-tosylamino-phenylethyl-chloromethyl ketone (TPCK) and the nicotinic acetylcholine receptor (nAChR)-specific inhibitor alpha-bungarotoxin (alphaBtx). Tosylphenylalanyl Chloromethyl Ketone 131-135 C-X-C motif chemokine ligand 8 Homo sapiens 10-14 19185596-9 2009 An NF-kappaB inhibitor, TPCK (N-Tosyl-L-Phenylalanine Chloromethyl Ketone) could suppress IL-8 production and secretion in response to S protein in PBMC and THP-1 cells and in HCoV-229E virus-infected PBMC. Tosylphenylalanyl Chloromethyl Ketone 30-73 C-X-C motif chemokine ligand 8 Homo sapiens 90-94 15618163-9 2005 The upregulation of ICAM-1, IL-6, and IL-8 was completely inhibited by pretreating the cells with an NF-kappaB activation inhibitor, l-1-tosylamido-2-phenylethyl chloromethyl ketone. Tosylphenylalanyl Chloromethyl Ketone 133-181 C-X-C motif chemokine ligand 8 Homo sapiens 38-42 12897563-11 2003 Treatment of cells with the NF-kappa B inhibitor N-tosyl-(L)-phenylalanine chloromethyl ketone, as well as with clarithromycin, reduced expression of IL-8 and NF-kappa B activity in a dose-dependent manner. Tosylphenylalanyl Chloromethyl Ketone 49-94 C-X-C motif chemokine ligand 8 Homo sapiens 150-154 9719033-6 1998 The IL-8 mRNA accumulation in response to P. intermedia LPS was inhibited by tosylphenyl-alanyl chloromethyl-ketone, an inhibitor of NF-kappaB activation, although the NF-kappaB activation itself was not altered by IFN-gamma. Tosylphenylalanyl Chloromethyl Ketone 77-115 C-X-C motif chemokine ligand 8 Homo sapiens 4-8