PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18980982-8 2008 A single ABT-888 dose (3 or 12.5 mg/kg) reduced intratumor PAR levels by >95%. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid 9-12 jumping translocation breakpoint Homo sapiens 59-62 19823047-7 2009 CONCLUSIONS: ABT-888 hits its therapeutic target by significantly reducing PAR levels and the ratio of PAR to PARP-1 in human tumor cells detected by immunohistochemistry. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid 13-16 jumping translocation breakpoint Homo sapiens 75-78 19823047-7 2009 CONCLUSIONS: ABT-888 hits its therapeutic target by significantly reducing PAR levels and the ratio of PAR to PARP-1 in human tumor cells detected by immunohistochemistry. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid 13-16 jumping translocation breakpoint Homo sapiens 103-106 18980982-9 2008 ABT-888 (1.56-25 mg/kg) significantly decreased PAR levels at 2 h post-dosing. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid 0-3 jumping translocation breakpoint Homo sapiens 48-51