PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26827495-6	2015	Because diclofenac is a non-specific antagonist of cyclooxygenases, it had been concluded that the prostaglandins mediate respiratory effects of IL-1beta in point of fact.	Diclofenac	8-18	interleukin 1 beta	Rattus norvegicus	145-153	
25511383-6	2015	Diclofenac pretreatment eliminated these respiratory effects of IL-1beta.	Diclofenac	0-10	interleukin 1 beta	Rattus norvegicus	64-72	
25428204-5	2015	A significant decrease in interleukin 1beta and tumor necrosis factor alpha occurred in tendons treated with phonophoresis+diclophenac+GNPs.	Diclofenac	123-134	interleukin 1 beta	Rattus norvegicus	26-75	
22619518-9	2012	A significant decrease was observed in expression of cytokines interleukin 1 beta in the three treatment groups, in comparison with untreated challenged tendons, although, in the group treated with diclofenac and GNP, results were similar to the control (1.732 +- 239) (P < 0.05).	Diclofenac	198-208	interleukin 1 beta	Rattus norvegicus	63-81	
22007590-9	2011	CONCLUSION: Acupuncture can down-regulate the expression of IL-1beta and TNF-alpha in osteoarthritic chondrocytes, and the regulating effect is the same as Diclofenac.	Diclofenac	156-166	interleukin 1 beta	Rattus norvegicus	60-68	
19798548-8	2009	In many respects, celecoxib (5 mg/kg) was as potent as diclofenac in decreasing the elevated levels of IL-6, IL-1beta, TNF-alpha, LTB(4), PGE(2), but lacked any significant effect on TXB(2) level.	Diclofenac	55-65	interleukin 1 beta	Rattus norvegicus	109-117	
17291994-4	2007	S-diclofenac administration downregulated expression of genes encoding enzymes which synthesize nitric oxide, prostanoids, and H2S; reduced plasma IL-1beta/TNF-alpha; and elevated plasma IL-10.	Diclofenac	2-12	interleukin 1 beta	Rattus norvegicus	147-155	
15111026-2	2004	Interleukin-1 beta, injected bilaterally into the dorsal hippocampus at a dose of 100 ng/side, significantly impaired working memory, and this impairment was attenuated by pretreatment with 10 mg/kg (s.c.) of diclofenac, a cyclooxygenase inhibitor.	Diclofenac	209-219	interleukin 1 beta	Rattus norvegicus	0-18	
30555323-7	2018	Diclofenac induced intestinal damage and inflammation, triggering an increase in tissue concentrations of tumor necrosis factor and interleukin-1beta, higher expression of TLR-2 and TLR-4, MyD88, NF-kappaB and activation of caspase-1.	Diclofenac	0-10	interleukin 1 beta	Rattus norvegicus	132-149	
32585792-2	2004	Interleukin-1 beta, injected bilaterally into the dorsal hippocampus at a dose of 100 ng/side, significantly impaired working memory, and this impairment was attenuated by pretreatment with 10 mg/kg (s.c.) of diclofenac, a cyclooxygenase inhibitor.	Diclofenac	209-219	interleukin 1 beta	Rattus norvegicus	0-18	
11525800-7	2001	Central administration of the prostaglandin antagonist, diclofenac (250 ug), but not ibuprofen, completely blocked the effect of IL-1beta on lung clearance of tumor cells.	Diclofenac	56-66	interleukin 1 beta	Rattus norvegicus	129-137