PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27761505-2	2016	In this data article we discuss an X-ray diffraction dataset that yielded the structure of PPARgamma LBD V290M mutant refined at 2.3 A resolution, that allowed building of 3D model of the receptor mutant with high confidence and revealed continuous well-defined electron density for the partial agonist diclofenac bound to hydrophobic pocket of the PPARgamma.	Diclofenac	303-313	peroxisome proliferator activated receptor gamma	Homo sapiens	91-100	
27014880-3	2016	In fact, diclofenac"s increased effect on spinal nociception and chronic neuro-inflammatory pain may be referred to: 1) its synergistic effects on peroxisome proliferator-activated receptor-gamma (PPAR- gamma) activation and prostaglandin synthesis inhibition (COX-2 inhibition); 2) its capacity of suppressing neuronal hyperexcitability through the blockage of neuronal K+ channels in a concentration-dependant manner; and 3) its facility to cross the blood-brain barrier.	Diclofenac	9-19	peroxisome proliferator activated receptor gamma	Homo sapiens	147-195	
27014880-3	2016	In fact, diclofenac"s increased effect on spinal nociception and chronic neuro-inflammatory pain may be referred to: 1) its synergistic effects on peroxisome proliferator-activated receptor-gamma (PPAR- gamma) activation and prostaglandin synthesis inhibition (COX-2 inhibition); 2) its capacity of suppressing neuronal hyperexcitability through the blockage of neuronal K+ channels in a concentration-dependant manner; and 3) its facility to cross the blood-brain barrier.	Diclofenac	9-19	peroxisome proliferator activated receptor gamma	Homo sapiens	197-208	
27761505-2	2016	In this data article we discuss an X-ray diffraction dataset that yielded the structure of PPARgamma LBD V290M mutant refined at 2.3 A resolution, that allowed building of 3D model of the receptor mutant with high confidence and revealed continuous well-defined electron density for the partial agonist diclofenac bound to hydrophobic pocket of the PPARgamma.	Diclofenac	303-313	peroxisome proliferator activated receptor gamma	Homo sapiens	349-358	
27099839-2	2016	OBJECTIVE: To investigate if adjuvant treatment of GD with the COX inhibitor and peroxisome proliferator-activated receptor-gamma (PPAR-gamma) antagonist diclofenac decreases the development of ophthalmopathy and if laboratory parameters are affected.	Diclofenac	154-164	peroxisome proliferator activated receptor gamma	Homo sapiens	131-141	
22231971-1	2011	OBJECTIVE: To report the use of sodium diclofenac, an antagonist of PPAR-gamma and cyclooxigenase-2 (COX-2) inhibitor in the treatment of mild to moderate Graves" ophthalmopathy.	Diclofenac	32-49	peroxisome proliferator activated receptor gamma	Homo sapiens	68-78	
17614770-12	2007	Diclofenac, an inhibitor of cyclooxygenases with antagonistic effects on PPAR-gamma, reduced the number of mature adipocytes by approximately 50%.	Diclofenac	0-10	peroxisome proliferator activated receptor gamma	Homo sapiens	73-83	
34843233-8	2021	Among environmental compounds, several molecules activated the PPARgamma of the four species similarly, e.g., phthalates (MEHP), perfluorinated compounds (PFOA, PFOS), and halogenated derivatives of BPA (TBBPA, TCBPA), but some of them like diclofenac and the organophosphorus compounds tri-o-tolyl phosphate and triphenyl phosphate were most active on zfPPARgamma.	Diclofenac	241-251	peroxisome proliferator activated receptor gamma	Homo sapiens	63-72