PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25940712-8 2015 Finally, we found that fludarabine and cyclophosphamide, frequently used before CART administration, downregulated IDO expression in lymphoma cells and improved the antitumor activity of CD19-CART in vivo. fludarabine 23-34 CD19 molecule Homo sapiens 187-191 22410752-12 2012 In summary, CD3/CD19-depleted HSCT with fludarabine-based RIC without serotherapy resulted in favorable patient survival, and rapid NK, DC and T-cell recovery. fludarabine 40-51 CD19 molecule Homo sapiens 16-20 15512822-0 2004 Fludarabine-induced apoptosis in CD19+/CD5+B-CLL cells is a direct and nurse-like-cell independent effect. fludarabine 0-11 CD19 molecule Homo sapiens 33-37 15512822-6 2004 Moreover, CD19+/CD5+B-CLL cells treated with fludarabine underwent apoptosis and this event was not related with the presence of NLCs whether treated or not with fludarabine. fludarabine 45-56 CD19 molecule Homo sapiens 10-14 15512822-7 2004 In conclusion, apoptosis induced by fludarabine in CD19+/CD5+B-CLL cells was due to a direct effect on these cells and not due to its effect in the NLCs. fludarabine 36-47 CD19 molecule Homo sapiens 51-55 35356197-4 2022 In this work we describe our institutional experience in a cohort of 38 pediatric and AYA patients with CD19-positive malignancy treated with lymphodepleting chemotherapy (fludarabine/cyclophosphamide) followed by a single infusion of CD19-CAR T cells (total infusions, n=39), including tisagenlecleucel (n=19; CD19/4-1BB) or on an institutional clinical trial (n=20; CD19/4-1BB; NCT03573700). fludarabine 172-183 CD19 molecule Homo sapiens 104-108 29749441-4 2018 The second aim was to evaluate the abilities of fludarabine (FDR) and mafosfamide (MFA; a metabolite of cyclophosphamide) to induce apoptosis of CD19-CAR-T cells via the use of Annexin V/propidium iodide double staining. fludarabine 48-59 CD19 molecule Homo sapiens 145-149 12756020-9 2003 The effects on the blood circulating myeloma compartments identified an increased reduction of CD19+ B cells and myeloma plasma cells in the fludarabine-arm. fludarabine 141-152 CD19 molecule Homo sapiens 95-99 10515887-7 1999 Mafosfamide significantly increased the apoptosis induced by fludarabine on CD19(+) cells (P =.007), but not on CD3(+) cells (P =. fludarabine 61-72 CD19 molecule Homo sapiens 76-80 35134115-0 2022 Fludarabine Exposure Predicts Outcome after CD19 CAR T-Cell Therapy in Children and Young Adults with Acute Leukemia. fludarabine 0-11 CD19 molecule Homo sapiens 44-48 35134115-6 2022 Exposure of fludarabine was shown to be a predictor for leukemia-free survival, B cell aplasia, and CD19-positive relapse following CAR T cell infusion. fludarabine 12-23 CD19 molecule Homo sapiens 100-104