PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12504799-5	2003	The CdA and CAFdA resistant cells displayed a deficiency in dCK activity (to <5%) while the Fara-A resistant cells showed only a minor reduction of dCK activity (20% reduction).	fludarabine	95-101	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	151-154	
3335008-1	1988	Previous studies have indicated that deoxycytidine kinase (dCK) is requisite and rate limiting in the phosphorylation of 1-beta-D-arabinofuranosylcytosine (ara-C) and 9-beta-D-arabinofuranosyl-2-fluoroadenine (F-ara-A) on the pathway to their respective cytotoxic 5"-triphosphates.	fludarabine	167-208	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	59-62	
3335008-1	1988	Previous studies have indicated that deoxycytidine kinase (dCK) is requisite and rate limiting in the phosphorylation of 1-beta-D-arabinofuranosylcytosine (ara-C) and 9-beta-D-arabinofuranosyl-2-fluoroadenine (F-ara-A) on the pathway to their respective cytotoxic 5"-triphosphates.	fludarabine	210-217	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	59-62	
16158821-1	2005	The cytotoxic action of the deoxyadenosine analogue 9-beta-D-arabinofuranosyl-2-fluoroadenine (F-ara-A) depends on the incorporation into DNA after being phosphorylated to F-ara-A triphosphate (F-ara-ATP) by deoxycytidine kinase (dCK).	fludarabine	52-93	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	230-233	
16158821-1	2005	The cytotoxic action of the deoxyadenosine analogue 9-beta-D-arabinofuranosyl-2-fluoroadenine (F-ara-A) depends on the incorporation into DNA after being phosphorylated to F-ara-A triphosphate (F-ara-ATP) by deoxycytidine kinase (dCK).	fludarabine	95-102	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	230-233	
16436271-1	2006	Deoxycytidine kinase (dCK) and deoxyguanosine kinase (dGK) catalyze the first step in the intracellular cascade of fludarabine (2-fluoroadenine-beta-D-arabinofuranoside) and cladribine (2-chlorodeoxyadenosine) phosphorylation, which leads to activation of these prodrugs, commonly used for treatment of chronic lymphocytic leukemia (CLL).	fludarabine	115-126	Calcium/calmodulin-dependent protein kinase II	Drosophila melanogaster	22-25