PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9129045-9 1997 Protein kinase C (PKC) activation with 100 nmol/L TPA (12-O-tetradecanoylphorbol 13-acetate) or incubation with interleukin-4 (10 ng/mL) prevented either dexamethasone- or fludarabine-induced proteolysis of PARP. fludarabine 172-183 interleukin 4 Homo sapiens 112-125 22072733-13 2012 CONCLUSION: We thus show that A771726 overcomes CD40L/IL-4-mediated resistance to fludarabine in CLL cells of untreated as well as clinically refractory CLL cells. fludarabine 82-93 interleukin 4 Homo sapiens 54-58 20716767-5 2010 A dye reduction cytotoxicity assay showed that IL-4 induced resistance to the cytotoxic drugs fludarabine and chlorambucil and to the novel p53-elevating agent nutlin 3. fludarabine 94-105 interleukin 4 Homo sapiens 47-51 18078872-7 2008 We found that the acute stimulation of PKC in IL-4-treated CLL cells by short-term incubation with PMA significantly increased hENT1 transport activity and favoured fludarabine-induced apoptosis. fludarabine 165-176 interleukin 4 Homo sapiens 46-50 18078872-9 2008 Our findings indicate that the combined treatment with IL-4 and PMA enhances hENT1 activity and specifically sensitizes CLL cells to undergo apoptosis induced by fludarabine. fludarabine 162-173 interleukin 4 Homo sapiens 55-59 20306682-0 2008 Modulation of IL-4 level by fludarabine and its relation to apoptosis in chronic B-cell lymphocytic leukemia. fludarabine 28-39 interleukin 4 Homo sapiens 14-18 11260081-6 2001 Fludarabine (F-ara-AMP, 0.1-100 micromol/ml) was able to downregulate the IL-4 content of CD8+ T cells, but not clonal B-cell IL-4. fludarabine 0-11 interleukin 4 Homo sapiens 74-78