PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28684418-7	2017	The HO-1 inducer cobalt protoporphyrin IX more efficiently attenuated PGE2 and IL-6 release in HG+IL-1beta-treated cells than in NG+IL-1beta-treated cells.	Cobalt	17-23	interleukin 1 beta	Homo sapiens	98-106	
28684418-7	2017	The HO-1 inducer cobalt protoporphyrin IX more efficiently attenuated PGE2 and IL-6 release in HG+IL-1beta-treated cells than in NG+IL-1beta-treated cells.	Cobalt	17-23	interleukin 1 beta	Homo sapiens	132-140	
24198853-6	2013	Particulate Co-alloy challenge induced >1000 pg/ml of IL-1beta and TNF-alpha, in monocytes and <50pg/mL IL-1beta and TNF-alpha in osteoclasts.	Cobalt	12-14	interleukin 1 beta	Homo sapiens	57-65	
24198853-6	2013	Particulate Co-alloy challenge induced >1000 pg/ml of IL-1beta and TNF-alpha, in monocytes and <50pg/mL IL-1beta and TNF-alpha in osteoclasts.	Cobalt	12-14	interleukin 1 beta	Homo sapiens	110-118	
24198853-7	2013	Cobalt ions induced >3000pg/mL IL-1beta and TNF-alpha in monocytes/macrophages and <50pg/mL IL-1beta and TNF-alpha in osteoclasts.	Cobalt	0-6	interleukin 1 beta	Homo sapiens	34-42	
24198853-7	2013	Cobalt ions induced >3000pg/mL IL-1beta and TNF-alpha in monocytes/macrophages and <50pg/mL IL-1beta and TNF-alpha in osteoclasts.	Cobalt	0-6	interleukin 1 beta	Homo sapiens	98-106	
22808498-8	2012	Orthodontic structures made from chromium-cobalt, or chromium-nickel alloys in the oral cavity of these patients increased the levels of MMP-2, IL-1beta and IL-6 in oral fluid.	Cobalt	42-48	interleukin 1 beta	Homo sapiens	144-152	
19844976-6	2010	Furthermore, cobalt, molybdenum ions, and Co-Cr-Mo alloy particles similarly induce elevated secretion of IL-1beta, TNFalpha, and IL-6.	Cobalt	13-19	interleukin 1 beta	Homo sapiens	106-114	
9186223-4	1997	Titanium, cobalt, and chromium at concentrations ranging from 0.01 to 100 ng/ml significantly enhanced the release of interleukin-1 beta and tumor necrosis factor-alpha by lipopolysaccharide stimulated human osteogenic sarcoma cells, whereas they did not alter the release of transforming growth factor-beta 1.	Cobalt	10-16	interleukin 1 beta	Homo sapiens	118-168	
31699531-9	2020	Increased Co was associated with decreased tumor necrosis factor alpha (rho = -0.56, P = .01) and interleukin 1 beta (rho = -0.48, P = .03).	Cobalt	10-12	interleukin 1 beta	Homo sapiens	98-116	
8968517-5	1996	We found that the release of IL-1 beta was enhanced by titanium, chromium and cobalt, the release of TNF-alpha was enhanced by titanium and chromium, and the release of IL-6 was enhanced by titanium.	Cobalt	78-84	interleukin 1 beta	Homo sapiens	29-38