PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21480614-10	2011	Canonical and alternative CBS assays suggest that maintaining the native heme ligation motif of wild-type Fe hCBS (Cys/His) is essential in maintaining maximal activity in Co hCBS.	Cobalt	172-174	cystathionine beta-synthase	Homo sapiens	26-29	
21480614-4	2011	Herein, we describe the characterization of a cobalt-substituted variant of hCBS (Co hCBS) in which CoPPIX replaces FePPIX (heme).	Cobalt	46-52	cystathionine beta-synthase	Homo sapiens	76-80	
21480614-4	2011	Herein, we describe the characterization of a cobalt-substituted variant of hCBS (Co hCBS) in which CoPPIX replaces FePPIX (heme).	Cobalt	46-52	cystathionine beta-synthase	Homo sapiens	85-89	
21480614-4	2011	Herein, we describe the characterization of a cobalt-substituted variant of hCBS (Co hCBS) in which CoPPIX replaces FePPIX (heme).	Cobalt	82-84	cystathionine beta-synthase	Homo sapiens	76-80	
21480614-4	2011	Herein, we describe the characterization of a cobalt-substituted variant of hCBS (Co hCBS) in which CoPPIX replaces FePPIX (heme).	Cobalt	82-84	cystathionine beta-synthase	Homo sapiens	85-89	
21480614-10	2011	Canonical and alternative CBS assays suggest that maintaining the native heme ligation motif of wild-type Fe hCBS (Cys/His) is essential in maintaining maximal activity in Co hCBS.	Cobalt	172-174	cystathionine beta-synthase	Homo sapiens	109-113	
21480614-10	2011	Canonical and alternative CBS assays suggest that maintaining the native heme ligation motif of wild-type Fe hCBS (Cys/His) is essential in maintaining maximal activity in Co hCBS.	Cobalt	172-174	cystathionine beta-synthase	Homo sapiens	175-179	
21184140-2	2011	Here we present another aspect of increased cobalt concentrations in the culture medium resulting in the production of cobalt protoporphyrin IX (CoPPIX), which was incorporated into heme proteins including membrane-bound cytochromes and an expressed human cystathionine beta-synthase (CBS).	Cobalt	44-50	cystathionine beta-synthase	Homo sapiens	256-283