PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
826600-4	1976	Pretreatment of rats with cobalt (30 min) produced the following changes in PCB actions on heme metabolism in liver: (a) augmentation of the porphyrinogenic effect of PCB, as determined by the total porphyrin content and ALAS activity; (b) augmentation of PCB inhibition of ALAD activity; and (c) blockade of induction of microsomal hemoprotein (cytochrome P-448).	Cobalt	26-32	5'-aminolevulinate synthase 1	Rattus norvegicus	221-225	
826600-7	1976	When cobalt was administered 24 h after PCB treatment, the magnitude of induction of ALAS by PCB was lowered, and there was a great reduction in microsomal hemoprotein and heme contents.	Cobalt	5-11	5'-aminolevulinate synthase 1	Rattus norvegicus	85-89	
3327431-8	1987	Acute treatment of rats with nickel, platinum, tin, antimony, bismuth, and cobalt results in induction of heme oxygenase, followed by decreased microsomal heme content and ALAS stimulation in the kidney.	Cobalt	75-81	5'-aminolevulinate synthase 1	Rattus norvegicus	172-176