PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30054507-0 2018 Histone deacetylase 8 protects human proximal tubular epithelial cells from hypoxia-mimetic cobalt- and hypoxia/reoxygenation-induced mitochondrial fission and cytotoxicity. Cobalt 92-98 histone deacetylase 8 Homo sapiens 0-21 30054507-4 2018 This study examined the role of HDAC8, which is the most distinct isoform of class I, in the hypoxia mimetic cobalt- and H/R-induced cytotoxicity of human proximal tubular HK-2 cells. Cobalt 109-115 histone deacetylase 8 Homo sapiens 32-37 30054507-9 2018 Collectively, this study shows that HDAC8 inhibits cytotoxicity induced by cobalt and H/R, in part, through suppressing DRP1 expression and mitochondrial fission. Cobalt 75-81 histone deacetylase 8 Homo sapiens 36-41