PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21400122-8 2012 Mice treated with midazolam had significantly lower serum IL-1beta (p=0.002), TNF-alpha (p=0.002), IL-6 (p=0.016), IL-10 (p=0.009), and TGF-beta (p=0.004) than saline-treated mice, with little impact on serum chemokine levels. Midazolam 18-27 tumor necrosis factor Mus musculus 78-87 30670973-6 2018 Mechanistically, midazolam suppressed tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) produced by LPS stimulated liver macrophages in vivo and bone marrow monocytes in vitro, and reduced the expression of major histocompatibility complex class II (MHC II), cluster of differentiation 40 and 86 (CD40 and CD86) on the cell surface. Midazolam 17-26 tumor necrosis factor Mus musculus 38-65 8031051-2 1994 Midazolam and 4"-chlorodiazepam significantly suppressed LPS (1-microgram/ml)-induced TNF activity in thioglycolate-elicited mouse macrophages. Midazolam 0-9 tumor necrosis factor Mus musculus 86-89 30670973-6 2018 Mechanistically, midazolam suppressed tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) produced by LPS stimulated liver macrophages in vivo and bone marrow monocytes in vitro, and reduced the expression of major histocompatibility complex class II (MHC II), cluster of differentiation 40 and 86 (CD40 and CD86) on the cell surface. Midazolam 17-26 tumor necrosis factor Mus musculus 67-76