PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26345937-6 2015 Midazolam significantly suppressed the IL-1beta-induced release of IL-6 in rat C6 glioma cells. Midazolam 0-9 interleukin 1 beta Rattus norvegicus 39-47 21682888-0 2011 Midazolam suppresses interleukin-1beta-induced interleukin-6 release from rat glial cells. Midazolam 0-9 interleukin 1 beta Rattus norvegicus 21-38 21682888-6 2011 In the present study, we investigated the effect of midazolam on IL-1beta-induced IL-6 release from C6 cells, and the mechanisms of this effect. Midazolam 52-61 interleukin 1 beta Rattus norvegicus 65-73 21682888-9 2011 RESULTS: Midazolam, but not propofol, inhibited IL-1beta-stimulated IL-6 release from C6 cells. Midazolam 9-18 interleukin 1 beta Rattus norvegicus 48-56 21682888-12 2011 Midazolam markedly suppressed IL-1beta-stimulated STAT3 phosphorylation without affecting the phosphorylation of p38 MAP kinase, SAPK/JNK or IkappaB. Midazolam 0-9 interleukin 1 beta Rattus norvegicus 30-38 21682888-13 2011 CONCLUSION: These results strongly suggest that midazolam inhibits IL-1beta-induced IL-6 release in rat C6 glioma cells via suppression of STAT3 activation. Midazolam 48-57 interleukin 1 beta Rattus norvegicus 67-75