PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21400122-8 2012 Mice treated with midazolam had significantly lower serum IL-1beta (p=0.002), TNF-alpha (p=0.002), IL-6 (p=0.016), IL-10 (p=0.009), and TGF-beta (p=0.004) than saline-treated mice, with little impact on serum chemokine levels. Midazolam 18-27 interleukin 1 beta Mus musculus 58-66 30670973-6 2018 Mechanistically, midazolam suppressed tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) produced by LPS stimulated liver macrophages in vivo and bone marrow monocytes in vitro, and reduced the expression of major histocompatibility complex class II (MHC II), cluster of differentiation 40 and 86 (CD40 and CD86) on the cell surface. Midazolam 17-26 interleukin 1 beta Mus musculus 82-99 30670973-6 2018 Mechanistically, midazolam suppressed tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) produced by LPS stimulated liver macrophages in vivo and bone marrow monocytes in vitro, and reduced the expression of major histocompatibility complex class II (MHC II), cluster of differentiation 40 and 86 (CD40 and CD86) on the cell surface. Midazolam 17-26 interleukin 1 beta Mus musculus 101-109 29667111-3 2018 In this study, the effects of four intravenous anesthetics (propofol, thiamylal sodium, midazolam, and ketamine) on IL-1beta secretion, ROS, and bacterial survival in S. aureus-infected RAW264.7 cells were evaluated. Midazolam 88-97 interleukin 1 beta Mus musculus 116-124 29667111-9 2018 However, thiamylal sodium and midazolam decreased IL-1beta mRNA and protein expression in a dose-dependent manner. Midazolam 30-39 interleukin 1 beta Mus musculus 50-58