PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11714877-8 2001 CYP2C6 mRNA levels were 4 times higher in midazolam-treated animals. Midazolam 42-51 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 Rattus norvegicus 0-6 29979512-2 2017 Tolbutamide, chlorzoxazone, theophylline, midazolam, omeprazole and dextromethorphanwere used as substrates of CYP2C6, CYP2E1, CYP1A2, CYP3A2, CYP2D1, and CYP2D2 to test the depressionimpact on drug metabolism. Midazolam 42-51 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 Rattus norvegicus 111-117 11911841-2 2002 Among the metabolic reactions studied, diclofenac 4-hydroxylation (DFH), dextromethorphan O-demethylation (DMOD) and midazolam 4-hydroxylation were specifically catalyzed by CYP2C6, CYP2D2 and CYP3A1/3A2, respectively. Midazolam 117-126 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 Rattus norvegicus 174-180 11911841-3 2002 These results suggest that diclofenac 4-hydroxylation, dextromethorphan O-demethylation and midazolam 4-hydroxylation are useful as catalytic markers of CYP2C6, CYP2D2 and CYP3A1/3A2, respectively. Midazolam 92-101 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 Rattus norvegicus 153-159 19219745-4 2009 Testosterone, propranolol, diclofenac, and midazolam were determined as specific substrates of rat CYP2C11, CYP2D2, CYP2C6, and CYP3A, respectively. Midazolam 43-52 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 Rattus norvegicus 116-122