PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25422586-0 2014 Inhibition of cardiac Kv1.5 potassium current by the anesthetic midazolam: mode of action. Midazolam 64-73 potassium voltage-gated channel subfamily A member 4 L homeolog Xenopus laevis 22-27 25422586-3 2014 Using the double-electrode voltage clamp technique, we studied pharmacological effects of midazolam on heterologously expressed Kv1.5 channels underlying atrial repolarizing current I(Kur). Midazolam 90-99 potassium voltage-gated channel subfamily A member 4 L homeolog Xenopus laevis 128-133 25422586-4 2014 Midazolam dose-dependently inhibited Kv1.5 current, yielding an IC50 of 17 muM in an HEK cell line and an IC50 of 104 muM in Xenopus oocytes. Midazolam 0-9 potassium voltage-gated channel subfamily A member 4 L homeolog Xenopus laevis 37-42 25422586-8 2014 Taken together, midazolam is an open channel inhibitor of cardiac Kv1.5 channels. Midazolam 16-25 potassium voltage-gated channel subfamily A member 4 L homeolog Xenopus laevis 66-71