PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22892444-7	2013	The metabolite formation rate of midazolam, a CYP3A4 substrate, in the permeation process of a monolayer linearly increased with an increase in the MOI of AdCYP3A4.	Midazolam	33-42	cytochrome P450 3A12	Canis lupus familiaris	46-52	
15030887-1	2004	The clinical pharmacokinetics of midazolam have been extensively studied, due to its high clearance by CYP3A4 and sensitivity to drug-drug interactions.	Midazolam	33-42	cytochrome P450 3A12	Canis lupus familiaris	103-109	
24273886-3	2013	The expression of CYP3A4 in the double-transfected cell line was determined by Western blot and its activity was detected by the metabolism assays of three substrates of CYP3A4, which were 7-benzyloxy-4-trifluoro-methylcoumarin (BFC), testosterone and midazolam.	Midazolam	252-261	cytochrome P450 3A12	Canis lupus familiaris	18-24	
24273886-3	2013	The expression of CYP3A4 in the double-transfected cell line was determined by Western blot and its activity was detected by the metabolism assays of three substrates of CYP3A4, which were 7-benzyloxy-4-trifluoro-methylcoumarin (BFC), testosterone and midazolam.	Midazolam	252-261	cytochrome P450 3A12	Canis lupus familiaris	170-176