PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11714877-7 2001 More strikingly, CYP2B1/2 mRNA levels were increased 22-fold upon midazolam treatment, leading to an 11- to 95-fold enhancement of CYP2B enzyme activity. Midazolam 66-75 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 17-23 11714877-11 2001 The induction of CYP2B1/2 mRNA levels by midazolam was dose-dependent (4.5-fold increase at 10 mg/kg). Midazolam 41-50 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 17-23 21925601-12 2011 Time-course activities of CYP2B1/2, 2D1, and 3A1 were also investigated by using bupropion, bufuralol, and midazolam as respective substrates. Midazolam 107-116 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 26-39