PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19857560-7 2010 In both cell types, MDZ-stimulated steroidogenesis in dose- and time-dependent manners, and induced the expression of PBR and StAR proteins, but had no effect on P450scc and 3beta-HSD expressions. Midazolam 20-23 translocator protein Mus musculus 118-121 35401924-4 2022 In this study, we evaluated the role of TSPO and its ligands PK11195 and Midazolam in LPS-activated BV-2 microglia cells involving mitophagy process and the nucleotide-binding domain-like receptor protein 3 (NLRP3) inflammasome activation. Midazolam 73-82 translocator protein Mus musculus 40-44 35401924-10 2022 Taken together, TSPO ligands PK11195 and Midazolam showed neuroprotective effects by reducing the inflammatory response of LPS-activated microglia, which may be related to the enhancement of mitophagy and the inhibition of NLRP3 inflammasome. Midazolam 41-50 translocator protein Mus musculus 16-20 33362467-0 2020 TSPO Ligands PK11195 and Midazolam Reduce NLRP3 Inflammasome Activation and Proinflammatory Cytokine Release in BV-2 Cells. Midazolam 25-34 translocator protein Mus musculus 0-4 22014182-10 2012 Pretreatment with the neurosteroid synthesis inhibitors finasteride, a 5alpha-reductase inhibitor, and a functional TSPO antagonist PK 11195, reduced the anticonvulsant action of midazolam. Midazolam 179-188 translocator protein Mus musculus 116-120 22014182-13 2012 CONCLUSION AND IMPLICATIONS: Enhanced endogenous neurosteroid synthesis, possibly mediated by an interaction with TSPO, contributed to the anticonvulsant action of midazolam. Midazolam 164-173 translocator protein Mus musculus 114-118 19857560-10 2010 These results highly indicated that MDZ-induced steroidogenesis in mouse Leydig cells via PKA and PKC pathways, along with the expression of PBR and StAR proteins. Midazolam 36-39 translocator protein Mus musculus 141-144