PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3987394-4 1985 Cefotaxime levels fall rapidly with a T 1/2 of 1.1 h, whereas ceftriaxone persists for 24 h with an unique T 1/2 of 8 h. Cefotaxime is eliminated by the kidneys and metabolized to desacetyl-cefotaxime resulting in a high total clearance. Cefotaxime 121-131 interleukin 1 receptor like 1 Homo sapiens 38-50 4028623-4 1985 After intravenous injection the cefotaxime serum kinetic parameters were as follows: plasma t 1/2, 2.31 +/- 0.20 hours; volume of distribution, 0.35 +/- 0.04 L/kg; total plasma clearance, 118.7 +/- 12.3 ml/min; and peritoneal clearance, 6.7 +/- 1.3 ml/min. Cefotaxime 32-42 interleukin 1 receptor like 1 Homo sapiens 92-103 3987394-4 1985 Cefotaxime levels fall rapidly with a T 1/2 of 1.1 h, whereas ceftriaxone persists for 24 h with an unique T 1/2 of 8 h. Cefotaxime is eliminated by the kidneys and metabolized to desacetyl-cefotaxime resulting in a high total clearance. Cefotaxime 121-131 interleukin 1 receptor like 1 Homo sapiens 107-117 6330019-3 1984 No significant differences in the pharmacokinetics of cefotaxime were observed between the various groups, with elimination half-life (T 1/2 beta) of cefotaxime ranging from 4.04 +/- 1.52 to 4.56 +/- 1.31 h. The desacetyl metabolite of cefotaxime was present in all post-dose serum samples, irrespective of the gestational age of the baby. Cefotaxime 150-160 interleukin 1 receptor like 1 Homo sapiens 135-145 6330019-3 1984 No significant differences in the pharmacokinetics of cefotaxime were observed between the various groups, with elimination half-life (T 1/2 beta) of cefotaxime ranging from 4.04 +/- 1.52 to 4.56 +/- 1.31 h. The desacetyl metabolite of cefotaxime was present in all post-dose serum samples, irrespective of the gestational age of the baby. Cefotaxime 150-160 interleukin 1 receptor like 1 Homo sapiens 135-145