PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17157873-5 2007 In an effort to elucidate the molecular mechanisms involved in enhanced activity, we carried out molecular dynamics simulations of ten MBL variants in complex with a cefotaxime intermediate. Cefotaxime 166-176 mannose-binding lectin family member 3, pseudogene Homo sapiens 135-138 32510322-3 2020 Here, we employ deep mutational scanning (DMS) to generate comprehensive single amino acid variant data on a major clinical MBL, VIM-2, by measuring the effect of thousands of VIM-2 mutants on the degradation of three representative classes of beta-lactams (ampicillin, cefotaxime, and meropenem) and at two different temperatures (25oC and 37oC). Cefotaxime 270-280 mannose-binding lectin family member 3, pseudogene Homo sapiens 124-127