PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22244271-6 2012 The reaction kinetics for the sub-structural moieties of TMP, 1,2,3-trimethoxybenzene (TMBz) and 2,4-diaminoprimidine (DAP), was evaluated to facilitate an understanding of the loss mechanisms. Trimethoprim 57-60 death associated protein Homo sapiens 119-122 12367702-1 2002 The diaminopyrimidine derivatives trimethoprim (TMP), pyrimethamine (PMA) and 2,4-diaminopyrimidine (2,4-DAP) are found to react readily and efficiently in an aqueous solution with p-benzoquinone (p-BQ) to form a colored product with an absorption optimum wavelength of about 500 nm. Trimethoprim 34-46 death associated protein Homo sapiens 105-108 12367702-1 2002 The diaminopyrimidine derivatives trimethoprim (TMP), pyrimethamine (PMA) and 2,4-diaminopyrimidine (2,4-DAP) are found to react readily and efficiently in an aqueous solution with p-benzoquinone (p-BQ) to form a colored product with an absorption optimum wavelength of about 500 nm. Trimethoprim 48-51 death associated protein Homo sapiens 105-108 32492634-4 2020 These steps eliminate PHZ contribution and the recovered spectrum is that of TMP and 2,6-DAP only where different methods can be applied to determine TMP and 2,6-DAP through this binary mixture spectrum. Trimethoprim 150-153 death associated protein Homo sapiens 89-92 32492634-5 2020 The first method to determine both components depends on measuring both TMP and 2,6-DAP through their first derivative (1DD) spectra at 244.70 and 259.60 nm for TMP and 2,6-DAP, respectively with concentration ranges of 4.00-24.00 mug/mL TMP and 4.00-26.00 mug/mL 2,6-DAP. Trimethoprim 72-75 death associated protein Homo sapiens 173-176 32492634-5 2020 The first method to determine both components depends on measuring both TMP and 2,6-DAP through their first derivative (1DD) spectra at 244.70 and 259.60 nm for TMP and 2,6-DAP, respectively with concentration ranges of 4.00-24.00 mug/mL TMP and 4.00-26.00 mug/mL 2,6-DAP. Trimethoprim 72-75 death associated protein Homo sapiens 173-176 32492634-5 2020 The first method to determine both components depends on measuring both TMP and 2,6-DAP through their first derivative (1DD) spectra at 244.70 and 259.60 nm for TMP and 2,6-DAP, respectively with concentration ranges of 4.00-24.00 mug/mL TMP and 4.00-26.00 mug/mL 2,6-DAP. Trimethoprim 161-164 death associated protein Homo sapiens 84-87 32492634-5 2020 The first method to determine both components depends on measuring both TMP and 2,6-DAP through their first derivative (1DD) spectra at 244.70 and 259.60 nm for TMP and 2,6-DAP, respectively with concentration ranges of 4.00-24.00 mug/mL TMP and 4.00-26.00 mug/mL 2,6-DAP. Trimethoprim 161-164 death associated protein Homo sapiens 84-87 32492634-6 2020 The second method depends on application of the isoabsorptive method which was used for TMP determination at its isoabsorptive point with 2,6-DAP at 242.64 nm with concentration range 1.00-20.00 mug/mL for TMP. Trimethoprim 88-91 death associated protein Homo sapiens 142-145 32492634-8 2020 Two multivariate methods were applied for determination of PHZ and TMP in presence of 2,6-DAP namely, Principle Component Regression (PCR) and Partial Least Squares (PLS). Trimethoprim 67-70 death associated protein Homo sapiens 90-93