PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35434034-0	2022	Metformin reverses tamoxifen resistance through the lncRNA GAS5-medicated mTOR pathway in breast cancer.	Tamoxifen	19-28	growth arrest specific 5	Homo sapiens	59-63	
34274167-0	2021	Retraction notice to "Downregulation of lncRNA GAS5 confers tamoxifen resistance by activating miR-222 in breast cancer" (Canc.	Tamoxifen	60-69	growth arrest specific 5	Homo sapiens	47-51	
33146930-8	2020	GAS5 overexpression promoted M1-like polarization of TAMs and inhibited M2-like polarization of TAMs.	Tamoxifen	53-57	growth arrest specific 5	Homo sapiens	0-4	
33146930-8	2020	GAS5 overexpression promoted M1-like polarization of TAMs and inhibited M2-like polarization of TAMs.	Tamoxifen	96-100	growth arrest specific 5	Homo sapiens	0-4	
33146930-11	2020	Our results demostrared that GAS5 overexpression inhibited M2-like polarization of TAMs by enhancing PTEN expression, thereby inhibiting cell proliferation and invasion by SMCC-7721 cells.	Tamoxifen	83-87	growth arrest specific 5	Homo sapiens	29-33	
29969658-0	2018	Downregulation of lncRNA GAS5 confers tamoxifen resistance by activating miR-222 in breast cancer.	Tamoxifen	38-47	growth arrest specific 5	Homo sapiens	25-29	
29969658-2	2018	This study investigates the role of lncRNA growth arrest-specific transcript 5 (GAS5) in tamoxifen resistance in breast cancer.	Tamoxifen	89-98	growth arrest specific 5	Homo sapiens	80-84	
29969658-6	2018	We further found that GAS5 overexpression enhanced cell sensitivity to tamoxifen in MCF-7R cells both in vitro and in vivo.	Tamoxifen	71-80	growth arrest specific 5	Homo sapiens	22-26	
29969658-7	2018	Moreover, GAS5 increased sensitivity of breast cancer cells to tamoxifen by serving as a molecular sponge for miR-222, contributing to suppression of phosphatase and tensin homologs (PTEN) (one endogenous target of miR-222).	Tamoxifen	63-72	growth arrest specific 5	Homo sapiens	10-14	
29969658-8	2018	Collectively, our study demonstrates that GAS5 enhances the efficacy of tamoxifen in the treatment of breast cancer and could be a novel prognostic biomarker.	Tamoxifen	72-81	growth arrest specific 5	Homo sapiens	42-46