PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6510549-8 1984 In addition, primary treatment with the antiestrogen tamoxifen prevents both receptor up-regulation and an enhanced rate of transcription or accumulation of vitellogenin mRNA on secondary hormonal exposure. Tamoxifen 53-62 a1-a Xenopus laevis 157-169 3736040-5 1986 Pre-injection with tamoxifen or 4-hydroxytamoxifen suppressed the estrogen-dependent induction of vitellogenin in serum. Tamoxifen 19-28 a1-a Xenopus laevis 98-110 3736040-6 1986 4-Hydroxytamoxifen also inhibited the induction of intracellular vitellogenin and its mRNA by estrogen suggesting that this metabolite of tamoxifen is able to inhibit estrogen-induced transcription of the vitellogenin genes. Tamoxifen 9-18 a1-a Xenopus laevis 65-77 3736040-6 1986 4-Hydroxytamoxifen also inhibited the induction of intracellular vitellogenin and its mRNA by estrogen suggesting that this metabolite of tamoxifen is able to inhibit estrogen-induced transcription of the vitellogenin genes. Tamoxifen 9-18 a1-a Xenopus laevis 205-217