PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8375774-0 1993 [Epinephrine in CPR--what is the optimal dose? Epinephrine 1-12 cytochrome p450 oxidoreductase Homo sapiens 16-19 7956410-0 1994 The effect of the total cumulative epinephrine dose administered during human CPR on hemodynamic, oxygen transport, and utilization variables in the postresuscitation period. Epinephrine 35-46 cytochrome p450 oxidoreductase Homo sapiens 78-81 7956410-1 1994 BACKGROUND: Studies evaluating the dose of epinephrine required to optimize return of spontaneous circulation and survival after CPR have shown that doses greater than recommended by advanced cardiac life support (ACLS) improve coronary perfusion pressure and short-term resuscitation rates. Epinephrine 43-54 cytochrome p450 oxidoreductase Homo sapiens 129-132 8541436-16 1995 This concept avoids overdosage in patients who had just collapsed shortly before initiation of CPR, attains higher levels of epinephrine in patients suffering from prolonged cardiac arrest, and takes into consideration that the effective epinephrine dose varies individually and increases with prolongation of the cardiac arrest interval. Epinephrine 238-249 cytochrome p450 oxidoreductase Homo sapiens 95-98 1336886-11 1992 It is suggested that supplementation with epinephrine during CPR may be unnecessary and the levels reached may be deleterious. Epinephrine 42-53 cytochrome p450 oxidoreductase Homo sapiens 61-64 1391364-6 1992 Higher doses of epinephrine for CPR seem to be recommendable only after prolonged cardiac arrest and/or during prolonged resuscitation. Epinephrine 16-27 cytochrome p450 oxidoreductase Homo sapiens 32-35 30511562-4 2019 Current neonatal resuscitation guidelines recommend administration of epinephrine once CPR has started at a dose of 0.01-0.03 mg/kg preferably given intravenously, with repeated doses every 3-5 min until return of spontaneous circulation. Epinephrine 70-81 cytochrome p450 oxidoreductase Homo sapiens 87-90 34265230-9 2021 Frequent epinephrine was associated with increased odds of survival with favorable neurobehavioral outcome (aOR 2.56; CI95 1.07, 6.14; p=0.036), with 66% of the association mediated by CPR duration. Epinephrine 9-20 cytochrome p450 oxidoreductase Homo sapiens 185-188 34265230-12 2021 Mediation analysis suggests improved outcomes are largely due to frequent epinephrine shortening duration of CPR. Epinephrine 74-85 cytochrome p450 oxidoreductase Homo sapiens 109-112 2504083-0 1989 Dose-dependent vasopressor response to epinephrine during CPR in human beings. Epinephrine 39-50 cytochrome p450 oxidoreductase Homo sapiens 58-61 2504083-1 1989 The optimal dose of epinephrine during CPR in human beings is unknown. Epinephrine 20-31 cytochrome p450 oxidoreductase Homo sapiens 39-42 3605543-1 1987 Reevaluation of current concepts in drug treatment during CPR was followed by some new recommendations concerning indication or dosage of drugs for CPR: While epinephrine remains the catecholamine of choice for cardiac resuscitation, application of buffer solutions should be performed with care. Epinephrine 159-170 cytochrome p450 oxidoreductase Homo sapiens 148-151 7214955-0 1981 Comparison of dopamine, dobutamine, and epinephrine in CPR. Epinephrine 40-51 cytochrome p450 oxidoreductase Homo sapiens 55-58 1639699-4 1992 Epinephrine, atropine, lidocaine, bretylium, and naloxone remain important drugs for consideration in CPR in most animals with cardiac arrest. Epinephrine 0-11 cytochrome p450 oxidoreductase Homo sapiens 102-105 4025969-0 1985 Beneficial effect of epinephrine infusion on cerebral and myocardial blood flows during CPR. Epinephrine 21-32 cytochrome p450 oxidoreductase Homo sapiens 88-91 4025969-2 1985 Our results with epinephrine infusion during CPR are consistent with this hypothesis. Epinephrine 17-28 cytochrome p450 oxidoreductase Homo sapiens 45-48 4025969-8 1985 Similar selective perfusion was sustained for 50 minutes of SCV-CPR with epinephrine, even when the onset of CPR was delayed five minutes. Epinephrine 73-84 cytochrome p450 oxidoreductase Homo sapiens 64-67 4025969-10 1985 In an infant animal model of CPR using conventional CPR in piglets, epinephrine also was found to increase cerebral and myocardial blood flows. Epinephrine 68-79 cytochrome p450 oxidoreductase Homo sapiens 29-32 4025969-10 1985 In an infant animal model of CPR using conventional CPR in piglets, epinephrine also was found to increase cerebral and myocardial blood flows. Epinephrine 68-79 cytochrome p450 oxidoreductase Homo sapiens 52-55 4025969-11 1985 These results show that administration of epinephrine benefits different age groups of different species with different modes of CPR; that benefits occur even with delayed onset of CPR which is associated with additional anoxia and acidosis; and that epinephrine administration is particularly effective in sustaining cerebral and coronary perfusion during prolonged CPR. Epinephrine 42-53 cytochrome p450 oxidoreductase Homo sapiens 129-132 4025969-11 1985 These results show that administration of epinephrine benefits different age groups of different species with different modes of CPR; that benefits occur even with delayed onset of CPR which is associated with additional anoxia and acidosis; and that epinephrine administration is particularly effective in sustaining cerebral and coronary perfusion during prolonged CPR. Epinephrine 42-53 cytochrome p450 oxidoreductase Homo sapiens 181-184 4025969-11 1985 These results show that administration of epinephrine benefits different age groups of different species with different modes of CPR; that benefits occur even with delayed onset of CPR which is associated with additional anoxia and acidosis; and that epinephrine administration is particularly effective in sustaining cerebral and coronary perfusion during prolonged CPR. Epinephrine 42-53 cytochrome p450 oxidoreductase Homo sapiens 181-184 17206434-6 2007 For condition after CPR we found an adrenaline/noradrenaline quotient of 2.81 +/- 5.8. Epinephrine 36-46 cytochrome p450 oxidoreductase Homo sapiens 20-23 19942396-12 2009 Advanced CPR: epinephrine dose known in 89.3 % (intravenous) and 34.3 % (tracheal). Epinephrine 14-25 cytochrome p450 oxidoreductase Homo sapiens 9-12 16563597-6 2006 After 2 min of CPR, epinephrine (adrenaline) (0. Epinephrine 20-31 cytochrome p450 oxidoreductase Homo sapiens 15-18