PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2558326-3 1989 Rats chronically cannulated in the right jugular veins showed a time-related increase in plasma corticosterone concentrations in response to intraperitoneal administration of IL-1 that lasted up to 4 h. In the same rats, plasma epinephrine (E) and norepinephrine (NE) concentrations were only slightly elevated (2-fold increase) at 30 min and at 1 h after IL-1 administration. Epinephrine 228-239 interleukin 1 complex Mus musculus 175-179 3023761-5 1986 Norepinephrine and epinephrine inhibited the capacity of gamma interferon and lipopolysaccharide to stimulate IL-1 production from mouse peritoneal macrophages. Epinephrine 3-14 interleukin 1 complex Mus musculus 110-114 3023761-8 1986 This, coupled with the capacity of norepinephrine and epinephrine to enhance intracellular cAMP levels in macrophages, strongly suggested that the catecholamine-induced suppression of IL-1 production may be mediated by elevated intracellular cAMP levels. Epinephrine 38-49 interleukin 1 complex Mus musculus 184-188