PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8257123-5	1993	The inhibitory effects of clavulanate, sulbactam, and tazobactam on the TEM-1 enzyme were substantially decreased in comparison with those on IRT-3, as indicated by the 50% inhibitory concentrations.	Tazobactam	54-64	hypothetical protein	Escherichia coli	72-77	
14534312-2	2003	In TEM-1 and SHV-1, the common class A beta-lactamases, alterations at Ser-130 confer resistance to inactivation by the beta-lactamase inhibitors, clavulanic acid, and tazobactam.	Tazobactam	168-178	hypothetical protein	Escherichia coli	3-8	
9044033-1	1997	MICs of piperacillin with tazobactam or sulbactam (4 mg/L) were higher at pH 6.5 than at pH 8.0 for Escherichia coli transconjugants with TEM-1 or TEM-2 enzymes, but not for those with TEM-3 or TEM-10 enzymes.	Tazobactam	26-36	hypothetical protein	Escherichia coli	138-143	
7640670-5	1995	The enzyme was as efficiently inhibited by clavulanic acid and tazobactam as the TEM-1 and TEM-2 beta-lactamases but more than the amoxycillin-clavulanic acid-resistant TRC-1 enzyme.	Tazobactam	63-73	hypothetical protein	Escherichia coli	81-86	
9527373-10	1997	The inhibitory efficacy of sulbactam, clavulanic acid and tazobactam over TEM-1 is inversely proportional to the amounts of enzyme produced.	Tazobactam	58-68	hypothetical protein	Escherichia coli	74-79	
1661596-3	1991	A combination with tazobactam was found to enhance the effectiveness of piperacillin against S. aureus producing penicillinase, E. coli producing TEM-1 or TEM 2 enzymes and class I beta-lactamase-derepressed isolates of E. cloacae, Serratia spp.	Tazobactam	19-29	hypothetical protein	Escherichia coli	146-151	
35134504-5	2022	METHODS: PIP MICs for E. coli isolates either hyperproducing TEM-1 because of promoter substitutions (n=4) or because of gene amplification (n=2) or producing an inhibitor resistant TEM-35 (IRT) (n=1) were determined using increasing concentrations of TAZ in a checkerboard setup.	Tazobactam	252-255	hypothetical protein	Escherichia coli	61-66	
31923568-4	2020	Increasing the tazobactam concentration from 4 mg/L to 16 mg/L restored TZP in vitro susceptibility among E. coli isolates expressing TEM-1, but had minimal impact on the susceptibility of K. pneumoniae to TZP.	Tazobactam	15-25	hypothetical protein	Escherichia coli	134-139	
24449780-1	2014	The post-beta-lactamase-inhibitor effect (PBLIE) of tazobactam combined with ceftolozane was evaluated by time-kill assays on two clinical Escherichia coli strains producing CTX-M-15 with or without TEM-1.	Tazobactam	52-62	hypothetical protein	Escherichia coli	199-204	
2558615-13	1989	In particular, piperacillin with tazobactam or clavulanic acid, but not with sulbactam, inhibited TEM-1, TEM-2, and SHV-1 enzymes.	Tazobactam	33-43	hypothetical protein	Escherichia coli	98-103