PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35134504-5	2022	METHODS: PIP MICs for E. coli isolates either hyperproducing TEM-1 because of promoter substitutions (n=4) or because of gene amplification (n=2) or producing an inhibitor resistant TEM-35 (IRT) (n=1) were determined using increasing concentrations of TAZ in a checkerboard setup.	Piperacillin	9-12	hypothetical protein	Escherichia coli	61-66	
3143575-7	1988	Piperacillin-resistant strains showed mostly TEM-1 activity, but also produced OXA-1 and chromosomal beta-lactamase.	Piperacillin	0-12	hypothetical protein	Escherichia coli	45-50	
2558615-13	1989	In particular, piperacillin with tazobactam or clavulanic acid, but not with sulbactam, inhibited TEM-1, TEM-2, and SHV-1 enzymes.	Piperacillin	15-27	hypothetical protein	Escherichia coli	98-103	
9044033-1	1997	MICs of piperacillin with tazobactam or sulbactam (4 mg/L) were higher at pH 6.5 than at pH 8.0 for Escherichia coli transconjugants with TEM-1 or TEM-2 enzymes, but not for those with TEM-3 or TEM-10 enzymes.	Piperacillin	8-20	hypothetical protein	Escherichia coli	138-143	
6397946-0	1984	Different mechanisms of TEM-1 and Oxa-1 mediated resistance to piperacillin in E. coli.	Piperacillin	63-75	hypothetical protein	Escherichia coli	24-29	
6397946-6	1984	Cell wall permeability of TEM-1 producing strains of E. coli to piperacillin was below the lower limit of detectability, but preincubation of the E. coli strains in piperacillin containing broth led to increased cell wall permeability.	Piperacillin	64-76	hypothetical protein	Escherichia coli	26-31	
6397946-6	1984	Cell wall permeability of TEM-1 producing strains of E. coli to piperacillin was below the lower limit of detectability, but preincubation of the E. coli strains in piperacillin containing broth led to increased cell wall permeability.	Piperacillin	165-177	hypothetical protein	Escherichia coli	26-31	
6397946-9	1984	The TEM-1 plasmid bearing strain inactivated piperacillin, and the degradation products (penicilloate) could be detected.	Piperacillin	45-57	hypothetical protein	Escherichia coli	4-9	
15781395-3	2005	Furthermore, most of the inhibitors enhanced the antibacterial activities of piperacillin (PIP) and ceftazidime (CAZ) particularly against TEM-1 and CTX-1 producing bacterial strains.	Piperacillin	77-89	hypothetical protein	Escherichia coli	139-144	
15781395-3	2005	Furthermore, most of the inhibitors enhanced the antibacterial activities of piperacillin (PIP) and ceftazidime (CAZ) particularly against TEM-1 and CTX-1 producing bacterial strains.	Piperacillin	91-94	hypothetical protein	Escherichia coli	139-144	
1661596-3	1991	A combination with tazobactam was found to enhance the effectiveness of piperacillin against S. aureus producing penicillinase, E. coli producing TEM-1 or TEM 2 enzymes and class I beta-lactamase-derepressed isolates of E. cloacae, Serratia spp.	Piperacillin	72-84	hypothetical protein	Escherichia coli	146-151	
1646771-2	1991	With TEM 1-producing E. coli, a correlation between specific beta-lactamase activity and the MIC of piperacillin and ampicillin-sulbactam was observed.	Piperacillin	100-112	hypothetical protein	Escherichia coli	5-10	
1802698-0	1991	Problems in interpretation of piperacillin susceptibility of TEM-1 producing Escherichia coli in the disk diffusion test.	Piperacillin	30-42	hypothetical protein	Escherichia coli	61-66