PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35362049-1 2022 Oils Rich in alpha-Linolenic Acid or Docosahexaenoic Acid Have Distinct Effects on Plasma Oxylipin and Adiponectin Concentrations and on Monocyte Bioenergetics in Women with Obesity. Docosahexaenoic Acids 37-57 adiponectin, C1Q and collagen domain containing Homo sapiens 103-114 34293124-0 2021 Oils Rich in alpha-Linolenic Acid or Docosahexaenoic Acid Have Distinct Effects on Plasma Oxylipin and Adiponectin Concentrations and on Monocyte Bioenergetics in Women with Obesity. Docosahexaenoic Acids 37-57 adiponectin, C1Q and collagen domain containing Homo sapiens 103-114 33482602-3 2021 While some studies have shown that marine-derived omega-3 fatty acids (eicosapentaenoic acid [EPA] and/or docosahexaenoic acid [DHA]) have effects on leptin and adiponectin in the context of inflammation, the extent of their effects remain unclear. Docosahexaenoic Acids 106-126 adiponectin, C1Q and collagen domain containing Homo sapiens 161-172 33482602-3 2021 While some studies have shown that marine-derived omega-3 fatty acids (eicosapentaenoic acid [EPA] and/or docosahexaenoic acid [DHA]) have effects on leptin and adiponectin in the context of inflammation, the extent of their effects remain unclear. Docosahexaenoic Acids 128-131 adiponectin, C1Q and collagen domain containing Homo sapiens 161-172 33482602-4 2021 The purpose of this systematic review was to summarize findings from randomized, controlled trials that measured effects of EPA+DHA supplementation on circulating levels of leptin and adiponectin to determine the state of the science. Docosahexaenoic Acids 128-131 adiponectin, C1Q and collagen domain containing Homo sapiens 184-195 27482523-6 2016 Fasting glucose, insulin resistance, hs-CRP and ba-PWVs were significantly higher and adiponectin and LDL particle size were significantly lower in the lower-DHA group than the higher-DHA group after adjusted for confounding factors. Docosahexaenoic Acids 158-161 adiponectin, C1Q and collagen domain containing Homo sapiens 86-97 30968772-4 2020 RESULT: The LCPUFAs eicosapentaenoic acid (C20:5 n-3, EPA) and docosahexaenoic acid (C22:6 n- 3, DHA) have a positive effect in diminishing liver steatosis, OS, and the levels of aspartate aminotransferase, alanine aminotransferase and pro-inflammatory cytokines, with improvement of insulin sensitivity and adiponectin levels. Docosahexaenoic Acids 63-83 adiponectin, C1Q and collagen domain containing Homo sapiens 308-319 28835131-7 2018 DHA slightly countered the actions of IL-1beta on CCL2, IL6 and ADIPOQ expression, though not on secretion of these adipokines. Docosahexaenoic Acids 0-3 adiponectin, C1Q and collagen domain containing Homo sapiens 64-70 28811832-0 2017 DHA increases adiponectin expression more effectively than EPA at relative low concentrations by regulating PPARgamma and its phosphorylation at Ser273 in 3T3-L1 adipocytes. Docosahexaenoic Acids 0-3 adiponectin, C1Q and collagen domain containing Homo sapiens 14-25 28811832-2 2017 Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) were reported to increase adiponectin by previous studies using a mixture of them. Docosahexaenoic Acids 0-20 adiponectin, C1Q and collagen domain containing Homo sapiens 85-96 28811832-2 2017 Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) were reported to increase adiponectin by previous studies using a mixture of them. Docosahexaenoic Acids 22-25 adiponectin, C1Q and collagen domain containing Homo sapiens 85-96 28811832-8 2017 RESULTS: Compared with the control, DHA increased cellular and secreted adiponectin at 50 and 100 mumol/L, while EPA increased them at 100 and 200 mumol/L. Docosahexaenoic Acids 36-39 adiponectin, C1Q and collagen domain containing Homo sapiens 72-83 28811832-9 2017 Adiponectin expressions in DHA treated groups were significantly higher than those in EPA treated groups at 50 and 100 mumol/L. Docosahexaenoic Acids 27-30 adiponectin, C1Q and collagen domain containing Homo sapiens 0-11 28811832-11 2017 GW9662 blocked DHA- and EPA-induced increases in PPARgamma as well as adiponectin. Docosahexaenoic Acids 15-18 adiponectin, C1Q and collagen domain containing Homo sapiens 70-81 28811832-13 2017 TNF-alpha blocked DHA-induced decrease in PPARgamma phosphorylation, which eventually led to a decrease in adiponectin. Docosahexaenoic Acids 18-21 adiponectin, C1Q and collagen domain containing Homo sapiens 107-118 28811832-15 2017 CONCLUSION: DHA compared with EPA led to a greater increase in cellular and secreted adiponectin at relative low concentrations by increasing PPARgamma expression and inhibiting its phosphorylation at Ser273. Docosahexaenoic Acids 12-15 adiponectin, C1Q and collagen domain containing Homo sapiens 85-96 29676540-11 2018 CONCLUSION: Eicosapentaenoic acid and docosahexaenoic acid supplementation may increase adiponectin and reduce TNF-alpha levels in this population group. Docosahexaenoic Acids 38-58 adiponectin, C1Q and collagen domain containing Homo sapiens 88-99 27281302-5 2016 RESULTS: Supplementation with DHA compared with supplementation with EPA led to a greater reduction in interleukin-18 (IL-18) (-7.0% +- 2.8% compared with -0.5% +- 3.0%, respectively; P = 0.01) and a greater increase in adiponectin (3.1% +- 1.6% compared with -1.2% +- 1.7%, respectively; P < 0.001). Docosahexaenoic Acids 30-33 adiponectin, C1Q and collagen domain containing Homo sapiens 220-231 25900100-4 2015 Adiponectin secretion was increased by treatment with fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and several fatty acids changed the cellular localization of adiponectin. Docosahexaenoic Acids 109-129 adiponectin, C1Q and collagen domain containing Homo sapiens 0-11 25900100-4 2015 Adiponectin secretion was increased by treatment with fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and several fatty acids changed the cellular localization of adiponectin. Docosahexaenoic Acids 131-134 adiponectin, C1Q and collagen domain containing Homo sapiens 0-11 25816805-6 2015 Furthermore, adiponectin was inversely correlated to the plasma levels of the two major n-3 PUFA docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) (r = -0.19, p < 0.001, and r = -0.30, p < 0.001, respectively). Docosahexaenoic Acids 119-122 adiponectin, C1Q and collagen domain containing Homo sapiens 13-24 25096818-10 2015 RESULTS: Fourteen months of treatment with DHA and EPA did not influence concentrations of leptin but adiponectin level was significantly decreased (P: 0.03). Docosahexaenoic Acids 43-46 adiponectin, C1Q and collagen domain containing Homo sapiens 102-113 25816805-9 2015 CONCLUSION: We found an elevated plasma adiponectin level, which was inversely associated with plasma levels of DHA and EPA at baseline. Docosahexaenoic Acids 112-115 adiponectin, C1Q and collagen domain containing Homo sapiens 40-51 18676720-5 2008 The expression of adipocyte fatty acid binding protein (aP2) and adiponectin in myoblasts stably expressing porcine PPARgamma was increased when docosahexaenoic acid (DHA) was added to the adipogenic medium. Docosahexaenoic Acids 145-165 adiponectin, C1Q and collagen domain containing Homo sapiens 65-76 25629558-8 2015 Eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and DHA combined with arachidonic acid (ARA) upregulated adiponectin secretion. Docosahexaenoic Acids 29-49 adiponectin, C1Q and collagen domain containing Homo sapiens 114-125 25629558-8 2015 Eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and DHA combined with arachidonic acid (ARA) upregulated adiponectin secretion. Docosahexaenoic Acids 51-54 adiponectin, C1Q and collagen domain containing Homo sapiens 114-125 25629558-8 2015 Eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and DHA combined with arachidonic acid (ARA) upregulated adiponectin secretion. Docosahexaenoic Acids 61-64 adiponectin, C1Q and collagen domain containing Homo sapiens 114-125 24332315-3 2014 DHA compared to EPA treatment led to a greater increase in adiponectin secretion and, conditioned media collected from DHA treated cells inhibited monocyte migration. Docosahexaenoic Acids 0-3 adiponectin, C1Q and collagen domain containing Homo sapiens 59-70 21164549-0 2010 Docosahexaenoic acid increases cellular adiponectin mRNA and secreted adiponectin protein, as well as PPARgamma mRNA, in 3T3-L1 adipocytes. Docosahexaenoic Acids 0-20 adiponectin, C1Q and collagen domain containing Homo sapiens 40-51 21164549-0 2010 Docosahexaenoic acid increases cellular adiponectin mRNA and secreted adiponectin protein, as well as PPARgamma mRNA, in 3T3-L1 adipocytes. Docosahexaenoic Acids 0-20 adiponectin, C1Q and collagen domain containing Homo sapiens 70-81 21164549-2 2010 Long-chain n-3 fatty acids eicosapentaenoic acid (20:5n-3; EPA) and docosahexaenoic acid (22:6n-3; DHA) may be involved in adiponectin regulation as they are potential ligands for peroxisome proliferator-activated receptor-gamma (PPARgamma), a key transcription factor for the adiponectin gene. Docosahexaenoic Acids 68-88 adiponectin, C1Q and collagen domain containing Homo sapiens 123-134 21164549-2 2010 Long-chain n-3 fatty acids eicosapentaenoic acid (20:5n-3; EPA) and docosahexaenoic acid (22:6n-3; DHA) may be involved in adiponectin regulation as they are potential ligands for peroxisome proliferator-activated receptor-gamma (PPARgamma), a key transcription factor for the adiponectin gene. Docosahexaenoic Acids 68-88 adiponectin, C1Q and collagen domain containing Homo sapiens 277-288 25240692-0 2015 Docosahexaenoic acid-enriched canola oil increases adiponectin concentrations: a randomized crossover controlled intervention trial. Docosahexaenoic Acids 0-20 adiponectin, C1Q and collagen domain containing Homo sapiens 51-62 21386858-7 2011 Moreover, red cell phosphatidylcholine docosahexaenoic acid correlated positively with adiponectin (r=0.290, P<0.05) but negatively with leptin (r=-0.252, P<0.05), insulin (r=-0.335, P<0.01) and insulin resistance (r=-0.322, P<0.01). Docosahexaenoic Acids 39-59 adiponectin, C1Q and collagen domain containing Homo sapiens 87-98 21490806-0 2011 Regulation of Serum Response Factor and Adiponectin by PPARgamma Agonist Docosahexaenoic Acid. Docosahexaenoic Acids 73-93 adiponectin, C1Q and collagen domain containing Homo sapiens 40-51 18579237-5 2009 In men, serum adiponectin correlated to levels of the content of EPA in platelets (r=0.26; p<0.01) and in granulocytes (r=0.23; p<0.01) and to the content of DHA in subcutaneous adipose tissue (r=0.15; p<0.05) and granulocytes (r=0.17; p<0.05). Docosahexaenoic Acids 164-167 adiponectin, C1Q and collagen domain containing Homo sapiens 14-25 18676720-6 2008 The response was positively related to DHA concentration and suggests that DHA may bind to and activate porcine PPARgamma, leading to increased expression of aP2 and adiponectin. Docosahexaenoic Acids 39-42 adiponectin, C1Q and collagen domain containing Homo sapiens 166-177 18676720-6 2008 The response was positively related to DHA concentration and suggests that DHA may bind to and activate porcine PPARgamma, leading to increased expression of aP2 and adiponectin. Docosahexaenoic Acids 75-78 adiponectin, C1Q and collagen domain containing Homo sapiens 166-177 18676720-5 2008 The expression of adipocyte fatty acid binding protein (aP2) and adiponectin in myoblasts stably expressing porcine PPARgamma was increased when docosahexaenoic acid (DHA) was added to the adipogenic medium. Docosahexaenoic Acids 167-170 adiponectin, C1Q and collagen domain containing Homo sapiens 65-76