PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20472557-0 2010 Novel derivative of benzofuran induces cell death mostly by G2/M cell cycle arrest through p53-dependent pathway but partially by inhibition of NF-kappaB. benzofuran 20-30 tumor protein p53 Homo sapiens 91-94 27101893-0 2016 Discovery and optimization of new benzofuran derivatives against p53-independent malignant cancer cells through inhibition of HIF-1 pathway. benzofuran 34-44 tumor protein p53 Homo sapiens 65-68 26842845-5 2016 This inhibition was due to the Profilin mediated attenuation of IkappaBalpha degradation, thereby preventing p65 nuclear translocation and low NF-kappaB DNA binding activity.Moreover, Profilin increases level of p53 in the presence of known inducers, such as doxorubicin, vinblastine, and benzofuran. benzofuran 289-299 tumor protein p53 Homo sapiens 212-215