PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7457013-1 1980 Inhalation of 4500 mg o-xylene by rats was found to produce adaptational and pathologic changes in the liver by the end of the 1st week, reflected in an increase in relative liver weight, shortening of the hexobarbital sleeping time, an increase in the concentration of cytochrome P-450, with a decrease in the activities of aniline hydroxylase and of aminopyrine N-demethylase. 2-xylene 22-30 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 270-286 7990171-3 1994 o-xylene decreased total pulmonary cytochrome P-450 content and aryl hydrocarbon hydroxylase (AHH) activity at all time points examined with maximal inhibition occurring at 3 h postdose. 2-xylene 0-8 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 35-51