PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23343619-0	2013	Activation of AMP-activated protein kinase by a plant-derived dihydroisosteviol in human intestinal epithelial cell.	dihydroisosteviol	62-79	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	14-42	
23343619-7	2013	Interestingly, this inhibitory effect of DHIS on CFTR was significantly (p<0.05) reduced by pretreatment with compound C, an AMPK inhibitor.	dihydroisosteviol	41-45	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	128-132	
23343619-9	2013	Western blot analysis showed that DHIS induced AMPK activation in T84 cells, but not in FRT-CFTR cells.	dihydroisosteviol	34-38	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	47-51	
23343619-10	2013	Our results indicate that DHIS inhibits CFTR-mediated chloride secretion in T84 cells, in part, by activation of AMPK activity.	dihydroisosteviol	26-30	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	113-117	
23343619-11	2013	DHIS therefore represents a novel candidate of AMPK activators.	dihydroisosteviol	0-4	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	47-51	
23343619-4	2013	In addition, effect of DHIS on AMP-activated protein kinase (AMPK) activation was investigated using Western blot analysis.	dihydroisosteviol	23-27	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	31-59	
23343619-4	2013	In addition, effect of DHIS on AMP-activated protein kinase (AMPK) activation was investigated using Western blot analysis.	dihydroisosteviol	23-27	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	61-65