PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23784744-0 2013 Naproxen and cromolyn as new glycogen synthase kinase 3beta inhibitors for amelioration of diabetes and obesity: an investigation by docking simulation and subsequent in vitro/in vivo biochemical evaluation. Cromolyn Sodium 13-21 glycogen synthase kinase 3 beta Mus musculus 29-59 23784744-1 2013 Naproxen and cromolyn were investigated as new inhibitors of glycogen synthase kinase-3beta (GSK-3beta) in an attempt to explain their hypoglycemic properties. Cromolyn Sodium 13-21 glycogen synthase kinase 3 beta Mus musculus 61-91 23784744-1 2013 Naproxen and cromolyn were investigated as new inhibitors of glycogen synthase kinase-3beta (GSK-3beta) in an attempt to explain their hypoglycemic properties. Cromolyn Sodium 13-21 glycogen synthase kinase 3 beta Mus musculus 93-102 23784744-3 2013 Both drugs not only were optimally fitted within a GSK-3beta binding pocket via several attractive interactions with key amino acids but also exhibited potent in vitro enzymatic inhibitory activities of IC50 1.5 and 2.0 microM for naproxen and cromolyn, respectively. Cromolyn Sodium 244-252 glycogen synthase kinase 3 beta Mus musculus 51-60 23784744-6 2013 It can be concluded that naproxen and cromolyn are novel GSK-3beta inhibitors and can help in management of diabetes and obesity. Cromolyn Sodium 38-46 glycogen synthase kinase 3 beta Mus musculus 57-66