PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23453072-0 2013 Design, synthesis and SAR investigation of thienosultam derivatives as ADAMTS-5 (aggrecanase-2) inhibitors. thienosultam 43-55 ADAM metallopeptidase with thrombospondin type 1 motif 5 Homo sapiens 71-79 23453072-0 2013 Design, synthesis and SAR investigation of thienosultam derivatives as ADAMTS-5 (aggrecanase-2) inhibitors. thienosultam 43-55 ADAM metallopeptidase with thrombospondin type 1 motif 5 Homo sapiens 81-94 23453072-1 2013 A series of 1,1-dioxothieno[2,3-d]isothiazole (thienosultam) derivatives were designed and synthesized as novel ADAMTS-5 inhibitors for an investigation into a side chain of thienosultam for the S1" pocket. thienosultam 47-59 ADAM metallopeptidase with thrombospondin type 1 motif 5 Homo sapiens 112-120 23453072-1 2013 A series of 1,1-dioxothieno[2,3-d]isothiazole (thienosultam) derivatives were designed and synthesized as novel ADAMTS-5 inhibitors for an investigation into a side chain of thienosultam for the S1" pocket. thienosultam 174-186 ADAM metallopeptidase with thrombospondin type 1 motif 5 Homo sapiens 112-120