PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 855909-2 1977 The inhibition by pancuronium of acetylcholinesterase (AChE) and of plasma cholinesterase (ChE) was investigated in vitro regarding a) the sensitivity of both enzymes; b) the mechanism and constants of inhibition; and c) the relationship between the neuromuscular blocking and the anticholinesterase activity of pancuronium. Pancuronium 18-29 acetylcholinesterase (Cartwright blood group) Homo sapiens 33-53 14564607-1 2000 PURPOSE: The kinetics of the inhibition of human plasma cholinesterase (ChE) and erythrocyte acetylcholinesterase (AChE) by alcuronium, atracurium, d-tubocurarine, pancuronium, pipecuronium, and vecuronium were studied in blood drawn from 35 surgical patients. Pancuronium 164-175 acetylcholinesterase (Cartwright blood group) Homo sapiens 93-113 14564607-1 2000 PURPOSE: The kinetics of the inhibition of human plasma cholinesterase (ChE) and erythrocyte acetylcholinesterase (AChE) by alcuronium, atracurium, d-tubocurarine, pancuronium, pipecuronium, and vecuronium were studied in blood drawn from 35 surgical patients. Pancuronium 164-175 acetylcholinesterase (Cartwright blood group) Homo sapiens 115-119 7643875-7 1995 In the patient controls, pancuronium 4 mg induced a severe neuromuscular block but not with 1 and 2 mg. Pancuronium dosages necessary to reverse severe OP-induced neuromuscular blockade produce a neuromuscular block when AChE activity is normal. Pancuronium 25-36 acetylcholinesterase (Cartwright blood group) Homo sapiens 221-225 7643875-7 1995 In the patient controls, pancuronium 4 mg induced a severe neuromuscular block but not with 1 and 2 mg. Pancuronium dosages necessary to reverse severe OP-induced neuromuscular blockade produce a neuromuscular block when AChE activity is normal. Pancuronium 104-115 acetylcholinesterase (Cartwright blood group) Homo sapiens 221-225 14564607-6 2000 The apparent inhibition constants (K(i)) of pancuronium (8.72 x 10(-8) M) and vecuronium (3.53 x 10(-7) M) for plasma ChE inhibition were lower than that of neostigmine (7.36 x 10(-7) M), whereas those of the six nondepolarizing NMBAs for erythrocyte AChE were markedly higher than that of neostigmine. Pancuronium 44-55 acetylcholinesterase (Cartwright blood group) Homo sapiens 251-255 855909-2 1977 The inhibition by pancuronium of acetylcholinesterase (AChE) and of plasma cholinesterase (ChE) was investigated in vitro regarding a) the sensitivity of both enzymes; b) the mechanism and constants of inhibition; and c) the relationship between the neuromuscular blocking and the anticholinesterase activity of pancuronium. Pancuronium 18-29 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-59 855909-4 1977 Pancuronium is a reversible inhibitor of both AChE and ChE. Pancuronium 0-11 acetylcholinesterase (Cartwright blood group) Homo sapiens 46-50 855909-9 1977 The inhibition of AChE and ChE is thought to be induced by a reversible binding of pancuronium to the anionic subsite of the active center, thus decreasing the formation of the primary enzyme-substrate complex. Pancuronium 83-94 acetylcholinesterase (Cartwright blood group) Homo sapiens 18-22 136679-0 1976 [Serum acetylcholinesterase changes after pancuronium administration]. Pancuronium 42-53 acetylcholinesterase (Cartwright blood group) Homo sapiens 7-27 136679-3 1976 The enzyme concentrations were lower in those patients that had also received Pancuronium, suggesting a cummulative inhibitory effect on serum acetylcholinesterase. Pancuronium 78-89 acetylcholinesterase (Cartwright blood group) Homo sapiens 143-163 1191483-5 1975 Pancuronium inhibition of the acetylcholinesterase in human red blood cells and from the electric eel was more than one thousand times weaker. Pancuronium 0-11 acetylcholinesterase (Cartwright blood group) Homo sapiens 30-50